Temperature Control Strategies of Atmospheric Plasma Jet for Tissue Treatment

Abstract

Besides the charged particles and neutral reactive species, the temperature effect is another significant issue needs to concern during the plasma treatment of biological tissue, which has effects on therapeutic efficacy and the risk of burns. Due to the influence of multiple factors on the temperature effect, it’s a complex nonlinear problem. In this study, temperature rise and distribution uniformity under different parameters and moving trajectories on porcine skin were investigated, and then a surface temperature control strategy was proposed. A 3-D electric motor control platform was constructed for the jet moving during the treatment. First, the effects of factors, such as distance, voltage, and flow rate on temperature variation over porcine skin surface, were analyzed, and the trends of temperature variation under single-factor influence were summarized. Then, the temperature distribution of fixed-point treatment and the temperature superposition effect on the tissue surface under different trajectories were explored, and a trajectory scheme for achieving homogeneous temperature distribution was proposed. Finally, a closed-loop control model was designed to achieve the control objectives of constant temperature holding over a certain surface area and resistance to high-temperature interference in real time. This control scheme also has reference significance for other surface treatments such as material processing.