{"title":"Updates in Osteosarcoma","authors":"Jeffrey N. Bryan DVM, MS, PhD","doi":"10.1016/j.cvsm.2023.12.007","DOIUrl":null,"url":null,"abstract":"","PeriodicalId":49380,"journal":{"name":"Veterinary Clinics of North America-Small Animal Practice","volume":"54 3","pages":"Pages 523-539"},"PeriodicalIF":1.9000,"publicationDate":"2023-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Veterinary Clinics of North America-Small Animal Practice","FirstCategoryId":"97","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0195561623001754","RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"VETERINARY SCIENCES","Score":null,"Total":0}
过去二十年来,犬骨肉瘤(OSA)的临床治疗几乎没有什么变化,主要依靠截肢和铂类化疗来控制疼痛和提高存活率。最近的进步为改善治疗效果带来了希望。基因组研究揭示了犬和人类 OSA 的共同基因异常。多维成像提供了宝贵的分期和预后信息。包括立体定向体放射治疗在内的保肢方法已成为常规。微波消融和组织切割等消融疗法前景看好。免疫疗法包括细胞疗法和免疫检查点抑制疗法。放射性药物可直接靶向 OSA 细胞。这些创新技术可能会改善 OSA 患犬的治疗和预后。
期刊介绍:
Veterinary Clinics of North America: Small Animal Practice offers you the most current information on the treatment of small animals such as cats and dogs, updates you on the latest advances, and provides a sound basis for choosing treatment options. Published bi-monthly—in January, March, May, July, September, November—each issue focuses on a single topic in small animal practice, including endocrinology, fluids and electrolytes, gastroenterology, infectious diseases, neurology, oncology, urology, respiratory issues , surgical information, small animal behavior, laboratory medicine, imaging methods, and nutrition.