Developments in Emerging Topical Drug Delivery Systems for Ocular Disorders.

Q3 Medicine
Suraj Mandal, Prabhakar Vishvakarma, Km Bhumika
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引用次数: 0

Abstract

According to the current information, using nano gels in the eyes have therapeutic benefits. Industry growth in the pharmaceutical and healthcare sectors has been filled by nanotechnology. Traditional ocular preparations have a short retention duration and restricted drug bioavailability because of the eye's architectural and physiological barriers, a big issue for physicians, patients, and chemists. In contrast, nano gels can encapsulate drugs within threedimensional cross-linked polymeric networks. Because of their distinctive structural designs and preparation methods, they can deliver loaded medications in a controlled and sustained manner, enhancing patient compliance and therapeutic efficacy. Due to their excellent drugloading capacity and biocompatibility, nano-gels outperform other nano-carriers. This study focuses on using nano gels to treat eye diseases and provides a brief overview of their creation and response to stimuli. Our understanding of topical drug administration will be advanced using nano gel developments to treat common ocular diseases such as glaucoma, cataracts, dry eye syndrome, bacterial keratitis, and linked medication-loaded contact lenses and natural active ingredients.

治疗眼疾的新兴局部给药系统的发展。
根据目前的信息,在眼部使用纳米凝胶具有治疗效果。纳米技术推动了制药和医疗保健行业的发展。由于眼睛的结构和生理障碍,传统的眼用制剂保留时间短,药物的生物利用度受到限制,这对医生、病人和化学家来说是个大问题。相比之下,纳米凝胶可将药物包裹在三维交联聚合物网络中。由于其独特的结构设计和制备方法,它们能以可控和持续的方式输送药物,提高患者的依从性和疗效。由于纳米凝胶具有出色的载药能力和生物相容性,其性能优于其他纳米载体。本研究的重点是利用纳米凝胶治疗眼疾,并简要介绍了纳米凝胶的形成及其对刺激的反应。利用纳米凝胶的发展来治疗青光眼、白内障、干眼综合症、细菌性角膜炎等常见眼部疾病,以及链接药物载荷的隐形眼镜和天然活性成分,将推进我们对局部用药的理解。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Current Drug Research Reviews
Current Drug Research Reviews Medicine-Psychiatry and Mental Health
CiteScore
3.70
自引率
0.00%
发文量
38
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