Estimation of serum and tissue level of interleukin-15 (IL-15) and IL-15 receptor alpha (IL-15Rα) in mycosis fungoides before and after phototherapy: An interventional cohort study

IF 2.5 4区医学 Q2 DERMATOLOGY

Photodermatology, photoimmunology & photomedicine Pub Date : 2023-12-29 DOI:10.1111/phpp.12938

Rania M Mogawer, Randa Youssef, Kholoud Helmy, Nourhan Emad, Olfat Shaker, Sarah Orabi

引用次数: 0

Abstract

Mycosis fungoides (MF) is a chronic, highly recurrent cutaneous T-cell lymphoma, whose pathogenesis has not yet been fully elucidated. Interleukin-15 was previously highlighted as a viability factor for cutaneous T-cell lymphoma with previous studies shedding light on its role in pathogenesis of MF and its plausibility as a potential therapeutic target.

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光疗前后真菌病患者血清和组织中白细胞介素-15（IL-15）及IL-15受体α（IL-15Rα）水平的估计：介入性队列研究

放线菌病（MF）是一种慢性、高复发性皮肤T细胞淋巴瘤，其发病机制尚未完全阐明。白细胞介素-15曾被强调为皮肤T细胞淋巴瘤的生存因子，先前的研究揭示了白细胞介素-15在MF发病机制中的作用及其作为潜在治疗靶点的可能性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Photodermatology, photoimmunology & photomedicine 医学-皮肤病学

CiteScore

4.40

自引率

7.70%

发文量

审稿时长

6-12 weeks

期刊介绍： The journal is a forum for new information about the direct and distant effects of electromagnetic radiation (ultraviolet, visible and infrared) mediated through skin. The divisions of the editorial board reflect areas of specific interest: aging, carcinogenesis, immunology, instrumentation and optics, lasers, photodynamic therapy, photosensitivity, pigmentation and therapy. Photodermatology, Photoimmunology & Photomedicine includes original articles, reviews, communications and editorials. Original articles may include the investigation of experimental or pathological processes in humans or animals in vivo or the investigation of radiation effects in cells or tissues in vitro. Methodology need have no limitation; rather, it should be appropriate to the question addressed.