Human ApoC3 overexpression aggravates hyperlipidemia but mitigates diet-induced coronary atherosclerotic disease in SR-BI and LDL receptor double knockout mice

IF 3.9 2区生物学 Q2 BIOCHEMISTRY & MOLECULAR BIOLOGY

Biochimica et biophysica acta. Molecular and cell biology of lipids Pub Date : 2023-12-30 DOI:10.1016/j.bbalip.2023.159449

Jiawei Liao , Yuhui Wang , Yao Wang , Jinjin Zhang , Feng Wu , George Liu , Wei Huang , Ying Zhang

引用次数: 0

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人载脂蛋白 C3 过度表达会加重 SR-BI 和低密度脂蛋白受体双基因敲除小鼠的高脂血症，但会减轻饮食诱发的冠状动脉粥样硬化疾病

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来源期刊

Biochimica et biophysica acta. Molecular and cell biology of lipids 生物-生化与分子生物学

CiteScore

11.00

自引率

2.10%

发文量

109

审稿时长

53 days

期刊介绍： BBA Molecular and Cell Biology of Lipids publishes papers on original research dealing with novel aspects of molecular genetics related to the lipidome, the biosynthesis of lipids, the role of lipids in cells and whole organisms, the regulation of lipid metabolism and function, and lipidomics in all organisms. Manuscripts should significantly advance the understanding of the molecular mechanisms underlying biological processes in which lipids are involved. Papers detailing novel methodology must report significant biochemical, molecular, or functional insight in the area of lipids.