Robotic Frameless Stereotactic Aspiration with Thrombolysis for Primary Pontine Hemorrhage: A Therapeutic Evaluation of a Retrospective Cohort Study.

IF 0.9 4区医学 Q4 CLINICAL NEUROLOGY

Journal of neurological surgery. Part A, Central European neurosurgery Pub Date : 2024-05-31 DOI:10.1055/a-2235-5453

Chongxi Xu, Wenbo He, Tong Yi, Hongtian Zhang, Jianguo Xu, Junpeng Ma

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引用次数: 0

Abstract

Background: There is still no consensus on whether primary pontine hemorrhage (PPH) should be managed conservatively or treated promptly via surgical evacuation of the hematoma. The purpose of this study was to assess the therapeutic effect of robotic frameless stereotactic aspiration with thrombolysis in the treatment of PPH.

Methods: A total of 39 patients with PPH treated between January 2012 and November 2016 were included in the study. Sixteen patients underwent frameless stereotactic surgical treatment (ST group) and 23 patients underwent conservative treatment (CT group). Clinical and radiologic parameters were assessed, and the patient outcomes were analyzed over a 6-month follow-up period.

Results: Surgical treatment did not result in any intracranial infections, or complications. Baseline characteristics did not significantly differ between the two groups. At discharge, the average Glasgow Coma Scale (GCS) score and the overall Glasgow Outcome Scale (GOS) score were significantly higher in the ST group compared to the CT group (p < 0.05). The mortality rate (GOS score 1) was significantly lower in the ST group (18.75%, 3/16) than in the CT group (52.17%, 12/23). For patients with hematoma volumes of 5 to 10 mL or GCS scores of 6 to 8, following treatment, the ST group exhibited markedly higher GOS scores in comparison to the CT group.

Conclusion: Our study suggests that robotic frameless stereotactic aspiration with thrombolysis is a safe and efficient method for the treatment of PPH. Patients with hematomas of 5 to 10 mL or GCS scores of 6 to 8 could benefit from surgery.

查看原文本刊更多论文

机器人无框架立体定向抽吸配合溶栓治疗原发性桥脑出血：一项回顾性队列研究的治疗评估。

导言：原发性桥脑出血（PPH）应采取保守治疗还是通过手术及时清除血肿仍存在争议。本研究旨在评估机器人无框架立体定向抽吸术联合溶栓治疗PPH的疗效：研究共纳入2012年1月至2016年11月期间的39例PPH患者。16例患者接受无框架立体定向手术治疗（ST组），23例患者接受保守治疗（CT组）。对临床和放射学参数进行了评估，并对患者6个月的随访结果进行了分析：手术治疗未导致任何颅内感染或并发症。两组患者的基线特征无明显差异。出院时，ST 组的格拉斯哥昏迷量表（GCS）平均评分和格拉斯哥结果量表（GOS）总评分明显高于 CT 组（P < 0.05）。ST组的死亡率（GOS评分1）（18.75%，3/16）明显低于CT组（52.17%，12/23）。对于血肿量为 5-10 毫升或 GCS 评分为 6-8 分的患者，ST 组在治疗后的格拉斯哥结果量表（GOS）评分明显高于 CT 组：总之，我们的研究表明，机器人无框架立体定向抽吸溶栓术是治疗 PPH 的一种安全有效的方法。血肿在5-10毫升或GCS评分在6-8分的患者可从手术中获益。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of neurological surgery. Part A, Central European neurosurgery CLINICAL NEUROLOGY-SURGERY

CiteScore

2.30

自引率

0.00%

发文量

期刊介绍： The Journal of Neurological Surgery Part A: Central European Neurosurgery (JNLS A) is a major publication from the world''s leading publisher in neurosurgery. JNLS A currently serves as the official organ of several national neurosurgery societies. JNLS A is a peer-reviewed journal publishing original research, review articles, and technical notes covering all aspects of neurological surgery. The focus of JNLS A includes microsurgery as well as the latest minimally invasive techniques, such as stereotactic-guided surgery, endoscopy, and endovascular procedures. JNLS A covers purely neurosurgical topics.