Abnormal Vaginal Cytology after Total Laparoscopic Hysterectomy in Patients with Cervical Intraepithelial Neoplasia.

IF 0.6 4区 医学 Q4 MEDICINE, RESEARCH & EXPERIMENTAL
Yumi Hibino, Mika Okazawa-Sakai, Takanori Yokoyama, Etsuko Fujimoto, Shinichi Okame, Norihiro Teramoto, Kazuhiro Takehara
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引用次数: 0

Abstract

To explore the incidence of abnormal vaginal cytology after total laparoscopic hysterectomy for the treatment of cervical intraepithelial neoplasia 3, we retrospectively analyzed the medical records of patients treated at NHO Shikoku Cancer Center (Japan) in 2014-2019. The cases of 99 patients who underwent a laparoscopic (n=36) or open (n=63) hysterectomy and postoperative follow-up were examined. Abnormal vaginal cytology was detected in 13.9% (5/36) of the laparoscopic-surgery (LS) group and 14.3% (9/63) of the open-surgery (OS) group. A vaginal biopsy was performed at the physicians' discretion; one LS patient and six OS patients were diagnosed with vaginal intraepithelial neoplasia. The cumulative incidence of abnormal vaginal cytology at 3 years post-hysterectomy was 21.4% (LS group) and 20.5% (OS group), a nonsignificant difference. A multivariate analysis showed that age > 50 years was the only independent risk factor for abnormal vaginal cytology among the covariates examined including age; body mass index; histories of vaginal delivery, abdominal surgery, and smoking; and surgical approach (hazard ratio 8.11; 95% confidence interval 1.73-37.98; p=0.01). These results suggest that the occurrence of abnormal vaginal cytology after a hysterectomy may not be influenced by the laparoscopic procedure but is associated with older age.

宫颈上皮内瘤变患者全腹腔镜子宫切除术后阴道细胞学检查异常
为了探讨为治疗宫颈上皮内瘤变3而进行全腹腔镜子宫切除术后阴道细胞学异常的发生率,我们回顾性分析了2014-2019年在NHO四国癌症中心(日本)接受治疗的患者的病历。我们对 99 例接受腹腔镜(36 例)或开腹(63 例)子宫切除术的患者的病例和术后随访情况进行了研究。腹腔镜手术(LS)组有13.9%(5/36)和开腹手术(OS)组有14.3%(9/63)发现阴道细胞学异常。阴道活检由医生决定进行,其中一名腹腔镜手术组患者和六名开腹手术组患者被诊断为阴道上皮内瘤变。子宫切除术后3年的阴道细胞学异常累积发生率为21.4%(LS组)和20.5%(OS组),差异不显著。多变量分析显示,在包括年龄、体重指数、阴道分娩史、腹部手术史、吸烟史和手术方式在内的协变量中,年龄大于 50 岁是阴道细胞学异常的唯一独立危险因素(危险比 8.11;95% 置信区间 1.73-37.98;P=0.01)。这些结果表明,子宫切除术后阴道细胞学异常的发生可能不受腹腔镜手术的影响,但与年龄较大有关。
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来源期刊
Acta medica Okayama
Acta medica Okayama 医学-医学:研究与实验
CiteScore
1.00
自引率
0.00%
发文量
110
审稿时长
6-12 weeks
期刊介绍: Acta Medica Okayama (AMO) publishes papers relating to all areas of basic and clinical medical science. Papers may be submitted by those not affiliated with Okayama University. Only original papers which have not been published or submitted elsewhere and timely review articles should be submitted. Original papers may be Full-length Articles or Short Communications. Case Reports are considered if they describe significant and substantial new findings. Preliminary observations are not accepted.
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