Modeling the impact of hospital beds and vaccination on the dynamics of an infectious disease

IF 1.9 4区 数学 Q2 BIOLOGY
Jyoti Maurya , Konstantin B. Blyuss , A.K. Misra
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引用次数: 0

Abstract

The unprecedented scale and rapidity of dissemination of re-emerging and emerging infectious diseases impose new challenges for regulators and health authorities. To curb the dispersal of such diseases, proper management of healthcare facilities and vaccines are core drivers. In the present work, we assess the unified impact of healthcare facilities and vaccination on the control of an infectious disease by formulating a mathematical model. To formulate the model for any region, we consider four classes of human population; namely, susceptible, infected, hospitalized, and vaccinated. It is assumed that the increment in number of beds in hospitals is continuously made in proportion to the number of infected individuals. To ensure the occurrence of transcritical, saddle–node and Hopf bifurcations, the conditions are derived. The normal form is obtained to show the existence of Bogdanov–Takens bifurcation. To validate the analytically obtained results, we have conducted some numerical simulations. These results will be useful to public health authorities for planning appropriate health care resources and vaccination programs to diminish prevalence of infectious diseases.

模拟医院床位和疫苗接种对传染病动态的影响
再次出现和新出现的传染病规模空前、传播迅速,给监管机构和卫生部门带来了新的挑战。要遏制此类疾病的传播,妥善管理医疗设施和疫苗是核心驱动力。在本研究中,我们通过建立一个数学模型来评估医疗设施和疫苗接种对控制传染病的统一影响。为了建立适用于任何地区的模型,我们考虑了四类人群,即易感人群、感染人群、住院人群和接种疫苗人群。假定医院床位数的增加与感染人数成正比。为确保出现跨临界、鞍节点和霍普夫分岔,导出了相关条件。得到的正态形式证明了 Bogdanov-Takens 分岔的存在。为了验证分析得出的结果,我们进行了一些数值模拟。这些结果将有助于公共卫生部门规划适当的医疗资源和疫苗接种计划,以减少传染病的流行。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Mathematical Biosciences
Mathematical Biosciences 生物-生物学
CiteScore
7.50
自引率
2.30%
发文量
67
审稿时长
18 days
期刊介绍: Mathematical Biosciences publishes work providing new concepts or new understanding of biological systems using mathematical models, or methodological articles likely to find application to multiple biological systems. Papers are expected to present a major research finding of broad significance for the biological sciences, or mathematical biology. Mathematical Biosciences welcomes original research articles, letters, reviews and perspectives.
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