Liver disease, heart failure, and 13-year mortality among Mexican American older adults: Nativity differences

IF 3.3 3区医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Annals of Epidemiology Pub Date : 2024-08-01 DOI:10.1016/j.annepidem.2023.12.004

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引用次数: 0

Abstract

Purpose

To examine nativity differences of co-occurring liver disease (LD) and heart failure (HF) on 13-year mortality among Mexican American older adults.

Methods

Prospective cohort study of 1601 Mexican Americans aged ≥ 75 years from the Hispanic Established Population for the Epidemiologic Study of the Elderly (2004/05–2016). Participants were grouped into four groups: no LD and no HF (n = 1138), LD only (n = 53), HF only (n = 382), and both LD and HF (n = 28). We used Cox proportional hazards regression model to estimate the hazard ratio (HR) and 95% confidence interval (CI) of death over time.

Results

The HR of death, as a function of HF only, was 1.32 (95% CI=1.07–1.62) among US-born and 1.36 (95% CI=1.04–1.78) among foreign-born participants, vs. those with no LD and no HF. Among foreign-born participants, the HR of death as a function of LD and HF was 3.39 (95% CI=1.65–6.93) vs. those without either. LD alone was not associated with mortality in either group. Among US-born, co-occurring LD and HF was not associated with mortality.

Conclusions

Foreign-born participants with both LD and HF were at higher risk of mortality over 13 years of follow up.

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原创文章：墨西哥裔美国老年人的肝病、心力衰竭和 13 年死亡率：种族差异

目的探讨并发肝病（LD）和心力衰竭（HF）对墨西哥裔美国老年人 13 年死亡率的影响。方法对西班牙裔老年人流行病学研究既定人群（2004/05-2016 年）中 1601 名年龄≥75 岁的墨西哥裔美国人进行前瞻性队列研究。参与者被分为四组：无 LD 和无 HF（n=1,138）、仅有 LD（n=53）、仅有 HF（n=382）以及既有 LD 又有 HF（n=28）。结果与无 LD 和无 HF 的参试者相比，仅 HF 一项的美国出生参试者死亡 HR 为 1.32（95% CI=1.07-1.62），外国出生参试者为 1.36（95% CI=1.04-1.78）。在外国出生的参与者中，与没有 LD 和 HF 的参与者相比，LD 和 HF 导致的死亡 HR 为 3.39（95% CI=1.65-6.93）。在这两组人群中，单独的低密度脂蛋白血症与死亡率无关。结论在13年的随访过程中，同时患有低密度脂蛋白血症和高密度脂蛋白血症的外国出生参与者的死亡风险较高。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Annals of Epidemiology 医学-公共卫生、环境卫生与职业卫生

CiteScore

7.40

自引率

1.80%

发文量

207

审稿时长

59 days

期刊介绍： The journal emphasizes the application of epidemiologic methods to issues that affect the distribution and determinants of human illness in diverse contexts. Its primary focus is on chronic and acute conditions of diverse etiologies and of major importance to clinical medicine, public health, and health care delivery.