Assessment of in vivo wound healing potentiality of Trapa natans L. leaves on different wound models in rat

IF 0.7 4区生物学 Q4 PLANT SCIENCES

Indian Journal of Traditional Knowledge Pub Date : 2023-12-13 DOI:10.56042/ijtk.v22i4.7197

{"title":"Assessment of in vivo wound healing potentiality of Trapa natans L. leaves on different wound models in rat","authors":"","doi":"10.56042/ijtk.v22i4.7197","DOIUrl":null,"url":null,"abstract":"The primary goal of this study was to assess the wound healing potentiality of Trapa natans L. Excision and incision models were used to evaluate wound healing activity. For the excision model experiment was conducted for 21 days and for the incision model experiment continued for 10 days. Experimental animals were divided into four groups, the control group received simple ointment, the animal of the standard group treated with 0.2% w/w soframycin ointment, and the test groups received T. natans extract ointment (2.5% w/w & 5% w/w). Wound healing was determined by the rate of contraction, the time required for epithelization, collagen cell formation, the amount of hydroxyproline present in the wound site, and woundbreaking strength. Experimental results of the test showed a comparatively higher rate of contraction, lesser epithelization period, and higher hydroxyproline amount present in the wound area. These results were strengthened by the histopathological studies of the healing area tissues. When the standard and test groups were compared to the control group, statistically significant data were found (p<0.001). The test group had better wound-healing properties as compared to the control group. From the result of this study, it was revealed that T. natans L. is an excellent herbal alternative for treating wounds.","PeriodicalId":56294,"journal":{"name":"Indian Journal of Traditional Knowledge","volume":"35 6","pages":""},"PeriodicalIF":0.7000,"publicationDate":"2023-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Indian Journal of Traditional Knowledge","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.56042/ijtk.v22i4.7197","RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"PLANT SCIENCES","Score":null,"Total":0}

引用次数: 0

Abstract

The primary goal of this study was to assess the wound healing potentiality of Trapa natans L. Excision and incision models were used to evaluate wound healing activity. For the excision model experiment was conducted for 21 days and for the incision model experiment continued for 10 days. Experimental animals were divided into four groups, the control group received simple ointment, the animal of the standard group treated with 0.2% w/w soframycin ointment, and the test groups received T. natans extract ointment (2.5% w/w & 5% w/w). Wound healing was determined by the rate of contraction, the time required for epithelization, collagen cell formation, the amount of hydroxyproline present in the wound site, and woundbreaking strength. Experimental results of the test showed a comparatively higher rate of contraction, lesser epithelization period, and higher hydroxyproline amount present in the wound area. These results were strengthened by the histopathological studies of the healing area tissues. When the standard and test groups were compared to the control group, statistically significant data were found (p<0.001). The test group had better wound-healing properties as compared to the control group. From the result of this study, it was revealed that T. natans L. is an excellent herbal alternative for treating wounds.

查看原文本刊更多论文

Trapa natans L.叶片对大鼠不同伤口模型的体内伤口愈合潜力评估

本研究的主要目的是评估 Trapa natans L 的伤口愈合潜力。切除模型实验持续 21 天，切口模型实验持续 10 天。实验动物分为四组，对照组使用简单的软膏，标准组动物使用 0.2% w/w 的索非霉素软膏，试验组动物使用纳坦菊提取物软膏（2.5% w/w 和 5% w/w）。伤口愈合由收缩率、上皮化所需时间、胶原细胞形成、伤口部位羟脯氨酸含量和伤口断裂强度决定。实验结果表明，收缩率相对较高，上皮化时间较短，伤口部位的羟脯氨酸含量较高。对愈合区组织的组织病理学研究也证实了这些结果。将标准组和试验组与对照组进行比较，发现数据具有统计学意义（P<0.001）。与对照组相比，试验组的伤口愈合性能更好。这项研究结果表明，T. natans L. 是一种治疗伤口的极佳草药替代品。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Indian Journal of Traditional Knowledge 生物-植物科学

CiteScore

1.80

自引率

37.50%

发文量

审稿时长

4-8 weeks

期刊介绍： Traditional knowledge" is employed to mean knowledge, innovations and practices of indigenous and local communities embodying traditional life-styles; the wisdom developed over many generations of holistic traditional scientific utilization of the lands, natural resources, and environment. It is generally passed down by word of mouth, from generation to generation and is, for the most part, undocumented. Traditional knowledge is valid and necessary, and awaits its currently relevant wider application for human benefit. National Institute of Science Communication and Information Resources, CSIR felt a need to document the recent developments and the information bygone in this area in the form of an interdisciplinary periodical. The Indian Journal of Traditional Knowledge will carry original research papers, review articles, short communications, etc. concerned with the observation and experimental investigation of the biological activities of the materials from plants, animals and minerals, used in the traditional health-care systems such as Ayurveda, Siddha, Yoga, Unani, Naturopathy, Homoeopathy, Folk-remedies, etc. As validation of indigenous claims it will cover Ethno-biology, Ethno-medicine, Ethno-pharmacology, Ethno-pharmacognosy & Clinical Studies on efficacy .