Association of Sarcoidosis and Primary Biliary Cirrhosis: A New Observation

Abstract

Sarcoidosis is a systemic disease of unknown etiology. It is characterized by the presence of noncaseating granulomatous lesions in the affected organs. Primary biliary cirrhosis (PBC) is a chronic autoimmune cholestatic hepatopathy characterized by destruction of the bile ducts and the presence of M2-type anti-mitochondrial antibodies [1]. The association of sarcoidosis and primary biliary cirrhosis reported here is rare. It poses a problem of histological differential diagnosis and raises the hypothesis of an etiopathogenic link between the two conditions [2]. We report the clinical case of a patient hospitalized in the internal medicine department of chu ibno rochd casablanca, who was diagnosed with a combination of sarcoidosis and primary biliary cirrhosis.