Patency of Drug-Coated versus Conventional Balloon Angioplasty for Hemodialysis Access Stenosis

IF 2 4区 医学 Q4 Medicine
Thanawat Anukanchanavera, Keerati Hongsakul, Phurich Janjindamai, Surasit Akkakrisee, Kittipitch Bannangkoon, S. Rookkapan, Ussanee Boonsrirat, Sarayut Geater
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引用次数: 0

Abstract

Purpose: This study aimed to evaluate the post-intervention target primary patency of drug-coated balloon angioplasty (DCBA) compared with conventional balloon angioplasty (CBA) in the treatment of the dysfunctional autogenous arteriovenous fistula (AVF) in a real-world clinical setting. Materials and Methods: This retrospective study included 24 patients with end-stage renal disease, who developed dysfunctional AVF during hemodialysis, and underwent endovascular treatment using CBA and DCBA from January 1, 2014, to June 30, 2021. The demographic data of patients and details regarding their fistula were recorded. Post-intervention target primary patency was analyzed. Results: Sixteen men and 8 women with an average age of 63.9 ± 14.2 years, who underwent 333 endovascular treatments in 57 target lesions of access were enrolled. DCBA was a protective factor for the treatment of a target lesion of dysfunctional access with an adjusted hazard ratio of 0.725 (95% confidence interval [CI]: 0.528–0.996; P = 0.047). According to the Weibull proportional hazards regression model, DCBA showed a longer post-intervention target primary patency than CBA. Conclusion: DCBA has better outcomes in terms of post-intervention target primary patency in the real-world treatment of dysfunctional autogenous AVF.
药物涂层与传统球囊血管成形术治疗血液透析通路狭窄的通畅性比较
目的:本研究旨在评估在实际临床环境中,药物涂层球囊血管成形术(DCBA)与传统球囊血管成形术(CBA)相比,在治疗功能障碍的自体动静脉瘘(AVF)方面的干预后目标原发性通畅率。材料和方法:这项回顾性研究纳入了 24 名终末期肾病患者,他们在血液透析期间出现了功能障碍性动静脉瘘,并在 2014 年 1 月 1 日至 2021 年 6 月 30 日期间接受了 CBA 和 DCBA 的血管内治疗。记录了患者的人口统计学数据和瘘管的详细情况。分析了干预后的目标原发性通畅率。结果:共纳入了 16 名男性和 8 名女性,平均年龄为(63.9 ± 14.2)岁,对 57 个通路靶病灶进行了 333 次血管内治疗。DCBA 是治疗通路功能障碍靶病变的保护因素,调整后的危险比为 0.725(95% 置信区间 [CI]:0.528-0.996;P = 0.047)。根据Weibull比例危险回归模型,DCBA比CBA显示出更长的干预后目标原发性通畅时间。结论:在真实世界中治疗功能障碍的自体动静脉瘘时,DCBA 在干预后目标原发性通畅率方面具有更好的疗效。
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来源期刊
Journal of the Belgian Society of Radiology
Journal of the Belgian Society of Radiology Medicine-Radiology, Nuclear Medicine and Imaging
CiteScore
0.60
自引率
5.00%
发文量
0
审稿时长
6-12 weeks
期刊介绍: The purpose of the Journal of the Belgian Society of Radiology is the publication of articles dealing with diagnostic and interventional radiology, related imaging techniques, allied sciences, and continuing education.
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