A quarter century of CANDES: The state of embryo technologies in companion animals, non-domestic and endangered species

Gabriela F. Mastromonaco
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Abstract

Companion animals, non-domestic and endangered species (CANDES) encompass a group of animals that do not include traditional livestock species (cattle, pigs, sheep, goats). Historically, lack of commercial interest or need resulted in a lag in the development and application of assisted reproductive technologies (ARTs) in CANDES. A number of factors impeded progress, including the species-specific nature of reproductive biology and difficulties accessing research material. The past 25 years have seen a growth in cell-based technologies (stem cell derivation, genome editing), offering a new horizon of possibilities to the current state-of-the-art for assisted reproduction in CANDES. This review highlights some of the challenges and successes in working with these diverse species.

四分之一世纪的 CANDES:伴侣动物、非家养动物和濒危物种的胚胎技术现状
伴侣动物、非家养动物和濒危物种(CANDES)包括一组不包括传统家畜物种(牛、猪、绵羊、山羊)的动物。从历史上看,由于缺乏商业利益或需求,CANDES 的辅助生殖技术(ART)的开发和应用滞后。许多因素阻碍了这一进程,包括生殖生物学的物种特异性和获取研究材料的困难。在过去的 25 年中,以细胞为基础的技术(干细胞衍生、基因组编辑)不断发展,为 CANDES 目前最先进的辅助生殖技术提供了新的可能性。本综述重点介绍了与这些不同物种合作过程中遇到的一些挑战和取得的成功。
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来源期刊
Theriogenology wild
Theriogenology wild Animal Science and Zoology, Veterinary Science
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