Pseudocarcinomatous Hyperplasia of Tubal Mucosa Associated With Chronic Salpingitis - Clinical And Pathological Challenge: A Case Report.

Snezhana Bulikj, Milica Kalamaras, Dzengis Jasar, Katerina Kubelka Sabit, Gligor Dimitrov, Mitko Ivanovski, Eva Palchevska, Jovana Topencharova
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Abstract

Pseudocarcinomatous hyperplasia of the tubal mucosa is a rare, reactive response to an underlying inflammatory or neoplastic process. We present a case of pseudocarcinomatous hyperplasia in a 26-year-old woman with clinical symptomatology of pelvic inflammatory disease, and a normal serum Ca 125-level (30 U/ml). The ultrasound finding showed presence of hydrosalpinx characterized with unilateral tubal enlargement in sausage-like shape that arose from the upper lateral margin of the uterus. The young age of the patient, presence of chronic inflammation, epithelial hyperplasia with unremarkable nuclear atypia and mitosis facilitated the right diagnosis. Pseudocarcinomatous hyperplasia can mimic neoplastic processes clinically and pathologically. Differential morphological and clinical features should be considered to ensure accurate diagnosis and proper management.

与慢性输卵管炎相关的输卵管粘膜假性癌增生--临床和病理挑战:病例报告。
输卵管粘膜假性癌变增生是一种罕见的、对潜在炎症或肿瘤过程的反应性反应。我们报告了一例假癌性增生病例,患者为一名 26 岁女性,临床症状为盆腔炎,血清 Ca 125 水平(30 U/ml)正常。超声检查结果显示存在输卵管积水,其特征是单侧输卵管增大,呈香肠状,从子宫上外侧缘长出。患者年龄较小,存在慢性炎症,上皮增生,核不典型性和有丝分裂不明显,因此诊断正确。假性癌增生在临床和病理上可模拟肿瘤过程。应考虑形态学和临床特征的鉴别,以确保诊断准确和处理得当。
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