Prognostic value of CHA₂DS₂-VASc score for the long-term cardiovascular events after coronary artery bypass grafting.

IF 0.5 4区医学 Q4 SURGERY

Turk Gogus Kalp Damar Cerrahisi Dergisi-Turkish Journal of Thoracic and Cardiovascular Surgery Pub Date : 2023-10-19 eCollection Date: 2023-10-01 DOI:10.5606/tgkdc.dergisi.2023.24964.

Abdulkadir Ercan, Orcun Gurbuz, Zekeriya Afsin Culhaoglu, Gencehan Kumtepe, Hakan Ozkan, Ahmet Yuksel, Serdar Ener

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引用次数: 0

Abstract

Background: This study aims to investigate the value of the CHA2DS2-VASc score in predicting long-term major cardiovascular events following coronary artery bypass grafting.

Methods: Between January 2008 and January 2010, a total of 559 patients (445 males, 114 females; mean age: 62.7±9.1 years; range, 35 to 84 years) who underwent elective coronary artery bypass grafting were retrospectively analyzed. At a mean of 10.7±3.1-year follow-up, major cardiovascular events were considered as the primary endpoint.

Results: The multivariate Cox hazard analysis identified the CHA₂DS₂-VASc score as an independent predictor of major cardiovascular events (hazard ratio: 1.615; 95% confidence interval: 1.038-2.511; p=0.034). The receiver operating characteristic curve analyses revealed that 3.5 was the most optimal cut-off value of the score predicting major cardiovascular events and the patients were divided into two groups accordingly. The Kaplan-Meier analysis demonstrated a significantly higher incidence of major cardiovascular events in proportion to a higher CHA₂DS₂-VASc score (p<0.001).

Conclusion: CHA₂DS₂-VASc score ≥4, which includes many risk factors for cardiovascular events, can be used as an independent predictor of long-term major cardiovascular events after coronary artery bypass grafting.

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CHA2DS2-VASc 评分对冠状动脉旁路移植术后长期心血管事件的预后价值。

背景本研究旨在探讨CHA2DS2-VASc评分在预测冠状动脉旁路移植术后长期主要心血管事件方面的价值：方法：对 2008 年 1 月至 2010 年 1 月期间接受择期冠状动脉搭桥术的 559 例患者（男性 445 例，女性 114 例；平均年龄：62.7±9.1 岁；年龄范围：35 岁至 84 岁）进行回顾性分析。在平均 10.7±3.1 年的随访中，主要心血管事件被视为主要终点：多变量 Cox 危险分析确定 CHA2DS2-VASc 评分是重大心血管事件的独立预测因子（危险比：1.615；95% 置信区间：1.038-2.511；P=0.034）。接收器操作特征曲线分析表明，3.5 是预测重大心血管事件的最佳分界值，并据此将患者分为两组。Kaplan-Meier 分析表明，CHA2DS2-VASc 评分越高，重大心血管事件的发生率越高（p 结论：CHA2DS2-VASc 评分越高，重大心血管事件的发生率越高：CHA2DS2-VASc评分≥4分包含了许多心血管事件的危险因素，可作为冠状动脉旁路移植术后长期主要心血管事件的独立预测指标。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Turk Gogus Kalp Damar Cerrahisi Dergisi-Turkish Journal of Thoracic and Cardiovascular Surgery SURGERY-

CiteScore

1.00

自引率

0.00%

发文量

审稿时长

3-8 weeks

期刊介绍： The Turkish Journal of Thoracic and Cardiovascular Surgery is an international open access journal which publishes original articles on topics in generality of Cardiac, Thoracic, Arterial, Venous, Lymphatic Disorders and their managements. These encompass all relevant clinical, surgical and experimental studies, editorials, current and collective reviews, technical know-how papers, case reports, interesting images, How to Do It papers, correspondences, and commentaries.