Preoperative risk factors of airway complications in adult lung transplant recipients: A systematic review and meta-analysis.

IF 0.5 4区 医学 Q4 SURGERY
Mahmut Subasi, Mustafa Duger
{"title":"Preoperative risk factors of airway complications in adult lung transplant recipients: A systematic review and meta-analysis.","authors":"Mahmut Subasi, Mustafa Duger","doi":"10.5606/tgkdc.dergisi.2023.25399","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>In this systematic review and meta-analysis, we aimed to identify recipient-related preoperative risk factors for airway complications following lung transplantation in adults.</p><p><strong>Methods: </strong>Articles published between November 1995 and February 2023 were searched by a thorough exploration of databases. Studies that addressed recipient-related risk factors for airway complications following adult lung transplantation, such as cohorts, case-control, or cross-sectional studies, were included. Fixed-effects or random-effects models were used to calculate the odds ratios (ORs) or mean differences (MDs) with 95% confidence interval (CI).</p><p><strong>Results: </strong>Twenty-one studies including a total of 38,321 recipients fulfilled the inclusion criteria. Based on the pooled analyses, taller height (MD=5.98, 95% CI: 5.69-6.27, <i>I<sup>2</sup></i>=57.32%), intraoperative mechanical ventilation (OR=1.83, 95% CI: 1.41-2.38, <i>I<sup>2</sup></i>=0%), male sex (OR=1.52, 95% CI: 1.33-1.74, <i>I<sup>2</sup></i> =15.91%), preoperative extracorporeal membrane oxygenation (OR=1.58, 95% CI: 1.1-2.26, <i>I<sup>2</sup></i>=41.47%), and preoperative steroid use (OR=1.21, 95% CI: 1.04-1.41, <i>I<sup>2</sup></i>=0%) elevated the risk of airway complications following lung transplantation.</p><p><strong>Conclusion: </strong>Taller height, intraoperative mechanical ventilation, male sex, preoperative extracorporeal membrane oxygenation, and preoperative steroid use can increase the risk of airway complications after lung transplantation. Identifying high-risk recipients or riskless situations can support the advancement of selective treatments or prevent the unnecessary avoidance of certain interventions.</p>","PeriodicalId":49413,"journal":{"name":"Turk Gogus Kalp Damar Cerrahisi Dergisi-Turkish Journal of Thoracic and Cardiovascular Surgery","volume":"31 4","pages":"517-529"},"PeriodicalIF":0.5000,"publicationDate":"2023-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10704524/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Turk Gogus Kalp Damar Cerrahisi Dergisi-Turkish Journal of Thoracic and Cardiovascular Surgery","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.5606/tgkdc.dergisi.2023.25399","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2023/10/1 0:00:00","PubModel":"eCollection","JCR":"Q4","JCRName":"SURGERY","Score":null,"Total":0}
引用次数: 0

Abstract

Background: In this systematic review and meta-analysis, we aimed to identify recipient-related preoperative risk factors for airway complications following lung transplantation in adults.

Methods: Articles published between November 1995 and February 2023 were searched by a thorough exploration of databases. Studies that addressed recipient-related risk factors for airway complications following adult lung transplantation, such as cohorts, case-control, or cross-sectional studies, were included. Fixed-effects or random-effects models were used to calculate the odds ratios (ORs) or mean differences (MDs) with 95% confidence interval (CI).

Results: Twenty-one studies including a total of 38,321 recipients fulfilled the inclusion criteria. Based on the pooled analyses, taller height (MD=5.98, 95% CI: 5.69-6.27, I2=57.32%), intraoperative mechanical ventilation (OR=1.83, 95% CI: 1.41-2.38, I2=0%), male sex (OR=1.52, 95% CI: 1.33-1.74, I2 =15.91%), preoperative extracorporeal membrane oxygenation (OR=1.58, 95% CI: 1.1-2.26, I2=41.47%), and preoperative steroid use (OR=1.21, 95% CI: 1.04-1.41, I2=0%) elevated the risk of airway complications following lung transplantation.

Conclusion: Taller height, intraoperative mechanical ventilation, male sex, preoperative extracorporeal membrane oxygenation, and preoperative steroid use can increase the risk of airway complications after lung transplantation. Identifying high-risk recipients or riskless situations can support the advancement of selective treatments or prevent the unnecessary avoidance of certain interventions.

成人肺移植受者气道并发症的术前风险因素:系统回顾和荟萃分析。
背景在这篇系统综述和荟萃分析中,我们旨在确定成人肺移植术后气道并发症的受者相关术前风险因素:方法:通过对数据库的全面检索,我们对 1995 年 11 月至 2023 年 2 月间发表的文章进行了检索。纳入了针对成人肺移植术后气道并发症受者相关风险因素的研究,如队列、病例对照或横断面研究。采用固定效应或随机效应模型计算几率比(ORs)或平均差(MDs)及95%置信区间(CI):共有 21 项研究符合纳入标准,研究对象共计 38,321 人。根据汇总分析,身高(MD=5.98,95% CI:5.69-6.27,I2=57.32%)、术中机械通气(OR=1.83,95% CI:1.41-2.38,I2=0%)、男性(OR=1.52,95% CI:1.33-1.74,I2=15.91%)、术前体外膜氧合(OR=1.58,95% CI:1.1-2.26,I2=41.47%)和术前使用类固醇(OR=1.21,95% CI:1.04-1.41,I2=0%)会增加肺移植术后气道并发症的风险:结论:身高、术中机械通气、男性、术前体外膜肺氧合和术前使用类固醇会增加肺移植术后气道并发症的风险。识别高风险受者或无风险情况有助于推进选择性治疗或防止不必要地避免某些干预措施。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
CiteScore
1.00
自引率
0.00%
发文量
98
审稿时长
3-8 weeks
期刊介绍: The Turkish Journal of Thoracic and Cardiovascular Surgery is an international open access journal which publishes original articles on topics in generality of Cardiac, Thoracic, Arterial, Venous, Lymphatic Disorders and their managements. These encompass all relevant clinical, surgical and experimental studies, editorials, current and collective reviews, technical know-how papers, case reports, interesting images, How to Do It papers, correspondences, and commentaries.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信