The impact of the Covid-19 vaccination policy in Mexico. A quasi-experimental effectiveness evaluation of a multi-vaccine strategy.

IF 2.4 4区医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Salud Publica De Mexico Pub Date : 2023-12-08 DOI:10.21149/14877

Sergio Bautista-Arredondo, Diego Cerecero-García, Fernando Macías-González, Tonatiuh Barrientos-Gutiérrez

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引用次数: 0

Abstract

Objective: To assess the impact of a vaccination campaign that administered five different technologies in a middle-income country with one of the largest Covid-19 epidemics.

Materials and methods: Using data from Mexico's Epidemiological Surveillance System for Viral Respiratory Disease (Sisver) and the design of the vaccine policy in Mexico as a natural experiment, we applied difference-in-differences econometric methods to assess the strategy's effectiveness on transmission, hospitalizations, and mortality rates among adults 60 to 64 years old in Mexico between April and June 2021.

Results: We estimated average effectiveness levels of 60.9% against confirmed cases of Covid-19. Vaccination also decreased hospitalizations and deaths by 62.7 and 62.6%, respectively. After adjusting for vaccination coverage, we found an impact of 79.1, 80.9, and 81.3% reduction in new cases, hospitalizations, and deaths among the vaccinated.

Conclusion: Despite the significant progress in our knowledge of Covid-19 vaccination effectiveness, the available evidence relies mostly on experiences from high-income countries. This study contributes to the scientific literature of Covid-19 vaccination effectiveness in a middle-income country with a multi-vaccine scheme.

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墨西哥 Covid-19 疫苗接种政策的影响。多种疫苗策略的准实验效果评估。

目的评估在中等收入国家开展的疫苗接种活动的影响，该活动采用了五种不同的疫苗接种技术，而墨西哥是 Covid-19 流行病流行最严重的国家之一：利用墨西哥病毒性呼吸道疾病流行病学监测系统（Sisver）的数据和墨西哥的疫苗政策设计作为自然实验，我们采用差分计量经济学方法评估了该策略在 2021 年 4 月至 6 月期间对墨西哥 60 至 64 岁成年人中的传播率、住院率和死亡率的影响：据估计，Covid-19确诊病例的平均有效率为60.9%。接种疫苗还可将住院率和死亡率分别降低 62.7% 和 62.6%。在对疫苗接种覆盖率进行调整后，我们发现接种疫苗对减少新发病例、住院人数和死亡人数的影响分别为 79.1%、80.9% 和 81.3%：结论：尽管我们对 Covid-19 疫苗接种效果的了解取得了重大进展，但现有证据主要依赖于高收入国家的经验。本研究为中等收入国家多种疫苗接种计划中 Covid-19 疫苗接种效果的科学文献做出了贡献。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Salud Publica De Mexico PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-

CiteScore

3.30

自引率

21.70%

发文量

审稿时长

34 weeks

期刊介绍： Salud Pública de México se crea en 1959 y comienza a publicarse bimestralmente a partir de 1961; en 1988 inicia una nueva época en la que se refuerza su carácter de publicación científica con evaluación por pares. Es una revista publicada por el Instituto Nacional de Salud Pública (INSP), organismo descentralizado de la Secretaría de Salud de México, dedicado a la investigación, docencia y difusión del conocimiento en salud pública. El INSP, de acuerdo con la normatividad internacional, otorga a la revista independencia editorial.