The relationship between echocardiographic parameters and albumin bilirubin score in patients with acute pulmonary thromboembolism.

IF 1.1 4区医学 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS

Perfusion-Uk Pub Date : 2025-01-01 Epub Date: 2023-12-12 DOI:10.1177/02676591231221706

Mert Evlice, İbrahim H Kurt

{"title":"The relationship between echocardiographic parameters and albumin bilirubin score in patients with acute pulmonary thromboembolism.","authors":"Mert Evlice, İbrahim H Kurt","doi":"10.1177/02676591231221706","DOIUrl":null,"url":null,"abstract":"Purpose: The Albumin-Bilirubin (ALBI) score is useful and easy-to-use for objectively assessing liver function. We investigated whether the ALBI score, a parameter indicating liver stiffness, congestion and fibrosis, has any relationship with echocardiographic parameters in patients with acute pulmonary thromboembolism (PTE).Material and methods: A total of 140 patients diagnosed with acute PTE were retrospectively analyzed. These patients were divided into three groups according to the hemodynamic severity of acute PTE: Group I [Low risk]; Group II [Submassive or intermediate-risk]; and Group III [Massive or high-risk]. Biochemical data obtained from venous blood samples taken at admission were analyzed. In addition, data were also analyzed from transthoracic echocardiography and pulmonary computed tomographic angiography performed at admission. ALBI, Bova, and PESI scores were calculated.Results: ALBI scores (-3.32 ± 0.21 vs -2.86 ± 0.15 vs -2.46 ± 0.2, p < .001) were statistically significantly higher in Group III than Groups I and II. There was a significant difference between the three groups in terms of echocardiographic parameters, and LVEF and TAPSE values tended to decrease from group I to group III. In multivariate linear regression analysis, sPAP, RV/RA diameter, and NT-pro-BNP were found to be significantly associated with the ALBI score. An ALBI score higher than -2.87 was associated with Bova stage II-III in patients with Group I and Group II PTE, with a sensitivity of 87% and a specificity of 62% (AUC = 0.804; 95% CI 0.713-0.895; p < .001).Conclusion: The ALBI score, which is a common, easy-to-use, and inexpensive method, may be beneficial to select intermediate and high-risk patients in patients with acute PTE. Additionally, it may have prognostic value in distinguishing low and intermediate-risk acute PTE patients.","PeriodicalId":49707,"journal":{"name":"Perfusion-Uk","volume":" ","pages":"92-102"},"PeriodicalIF":1.1000,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Perfusion-Uk","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1177/02676591231221706","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2023/12/12 0:00:00","PubModel":"Epub","JCR":"Q4","JCRName":"CARDIAC & CARDIOVASCULAR SYSTEMS","Score":null,"Total":0}

引用次数: 0

Abstract

Purpose: The Albumin-Bilirubin (ALBI) score is useful and easy-to-use for objectively assessing liver function. We investigated whether the ALBI score, a parameter indicating liver stiffness, congestion and fibrosis, has any relationship with echocardiographic parameters in patients with acute pulmonary thromboembolism (PTE).

Material and methods: A total of 140 patients diagnosed with acute PTE were retrospectively analyzed. These patients were divided into three groups according to the hemodynamic severity of acute PTE: Group I [Low risk]; Group II [Submassive or intermediate-risk]; and Group III [Massive or high-risk]. Biochemical data obtained from venous blood samples taken at admission were analyzed. In addition, data were also analyzed from transthoracic echocardiography and pulmonary computed tomographic angiography performed at admission. ALBI, Bova, and PESI scores were calculated.

Results: ALBI scores (-3.32 ± 0.21 vs -2.86 ± 0.15 vs -2.46 ± 0.2, p < .001) were statistically significantly higher in Group III than Groups I and II. There was a significant difference between the three groups in terms of echocardiographic parameters, and LVEF and TAPSE values tended to decrease from group I to group III. In multivariate linear regression analysis, sPAP, RV/RA diameter, and NT-pro-BNP were found to be significantly associated with the ALBI score. An ALBI score higher than -2.87 was associated with Bova stage II-III in patients with Group I and Group II PTE, with a sensitivity of 87% and a specificity of 62% (AUC = 0.804; 95% CI 0.713-0.895; p < .001).

Conclusion: The ALBI score, which is a common, easy-to-use, and inexpensive method, may be beneficial to select intermediate and high-risk patients in patients with acute PTE. Additionally, it may have prognostic value in distinguishing low and intermediate-risk acute PTE patients.

查看原文本刊更多论文

急性肺血栓栓塞症患者超声心动图参数与白蛋白胆红素评分之间的关系。

目的：白蛋白-胆红素（ALBI）评分对于客观评估肝功能非常有用且易于使用。我们研究了 ALBI 评分（表示肝脏僵硬、充血和纤维化的参数）与急性肺血栓栓塞症（PTE）患者的超声心动图参数是否有任何关系：回顾性分析了140例急性肺血栓栓塞症患者。根据急性 PTE 的血流动力学严重程度将这些患者分为三组：I 组[低风险]；II 组[亚严重或中风险]；III 组[严重或高风险]。分析了从入院时采集的静脉血样本中获得的生化数据。此外，还分析了入院时进行的经胸超声心动图和肺部计算机断层扫描血管造影的数据。计算了ALBI、Bova和PESI评分：第三组的 ALBI 评分（-3.32 ± 0.21 vs -2.86 ± 0.15 vs -2.46 ± 0.2，P < .001）明显高于第一组和第二组。在超声心动图参数方面，三组之间存在明显差异，从第一组到第三组，LVEF 和 TAPSE 值呈下降趋势。在多变量线性回归分析中，发现 sPAP、RV/RA 直径和 NT-pro-BNP 与 ALBI 评分显著相关。在I组和II组PTE患者中，ALBI评分高于-2.87与Bova II-III期相关，敏感性为87%，特异性为62%（AUC = 0.804; 95% CI 0.713-0.895; p < .001）：ALBI评分是一种常见、易于使用且成本低廉的方法，可能有助于在急性PTE患者中选择中危和高危患者。此外，它在区分低危和中危急性 PTE 患者方面可能具有预后价值。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Perfusion-Uk 医学-外周血管病

CiteScore

3.00

自引率

8.30%

发文量

203

审稿时长

6-12 weeks

期刊介绍： Perfusion is an ISI-ranked, peer-reviewed scholarly journal, which provides current information on all aspects of perfusion, oxygenation and biocompatibility and their use in modern cardiac surgery. The journal is at the forefront of international research and development and presents an appropriately multidisciplinary approach to perfusion science.