Risk Factors for Relapse of Prostate Cancerafter Radical Prostatectomy in Chinese Population.

IF 1.5 4区医学 Q3 UROLOGY & NEPHROLOGY

Urology Journal Pub Date : 2023-12-13 DOI:10.22037/uj.v20i.7758

Pinghong You, Liuting Xu, Liangyou Tang, Chunyang Wang

引用次数: 0

Abstract

To analyze the risk factors for the relapse of prostate cancer (PC) after radical prostatectomy (RP) and build a nomogram as a predictive model. Materials andMethods: The patients who underwent PR from March 2019 to February 2022 were retrospectively enrolled in our hospital's case system. During the follow-up process, two consecutive prostate-specific antigens (PSA) ≥0.2 μg/L were performed. And needle biopsy was performed to further determine whether the patient had prostate cancer recurrence. According to the follow-up results, the patients were divided into non-relapsed and relapsed groups.The related parameters of the two groups were collected. Independent risk factors for postoperative recurrence were determined using a Cox proportional hazards regression model. Statistical software, R, was used to build nomograms. R software was used to construct a nomogram, and the prediction effect of the nomogram was evaluated by the calibration curve and the area under the ROC curve (AUC).

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中国人群前列腺癌根治术后复发的风险因素

目的：分析根治性前列腺切除术（RP）后前列腺癌（PC）复发的风险因素，并建立预测模型提名图。材料与方法：在我院病例系统中回顾性登记了2019年3月至2022年2月期间接受前列腺癌根治术的患者。在随访过程中，连续两次前列腺特异性抗原（PSA）≥0.2 μg/L。并进行针刺活检，以进一步确定患者是否有前列腺癌复发。根据随访结果将患者分为未复发组和复发组，并收集两组患者的相关指标。采用 Cox 比例危险回归模型确定术后复发的独立危险因素。使用 R 统计软件构建提名图。使用 R 软件构建提名图，并通过校准曲线和 ROC 曲线下面积（AUC）评估提名图的预测效果。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Urology Journal UROLOGY & NEPHROLOGY-

CiteScore

2.60

自引率

6.70%

发文量

审稿时长

6-12 weeks

期刊介绍： As the official journal of the Urology and Nephrology Research Center (UNRC) and the Iranian Urological Association (IUA), Urology Journal is a comprehensive digest of useful information on modern urology. Emphasis is on practical information that reflects the latest diagnostic and treatment techniques. Our objectives are to provide an exceptional source of current and clinically relevant research in the discipline of urology, to reflect the scientific work and progress of our colleagues, and to present the articles in a logical, timely, and concise format that meets the diverse needs of today’s urologist. Urology Journal publishes manuscripts on urology and kidney transplantation, all of which undergo extensive peer review by recognized authorities in the field prior to their acceptance for publication. Accordingly, original articles, case reports, and letters to editor are encouraged.