{"title":"Therapeutic Approaches to Increase the Survival Rate of Cancer Patients\nin the Younger and Older Population","authors":"Tharrun Paul, Kanagaraj Palaniyandi, Dhanavathy Gnanasampanthapandian","doi":"10.2174/0118746098241507231127114248","DOIUrl":null,"url":null,"abstract":"\n\nVarious developments have been observed in the treatment of cancer patients, such as\nhigher survival rates and better treatment outcomes. However, expecting similar outcomes in\nolder patients remains a challenge. The main reason for this conclusion is the exclusion of older\npeople from clinical trials for cancer drugs, as well as other factors, such as comorbidity, side\neffects, age-related frailties and their willingness to undergo multiple treatments. However, the\ndiscovery of new techniques and drug combinations has led to a significant improvement in the\nsurvival of the elderly population after the onset of the disease. On the other hand, cancer treatments have not become more complex for the younger population when compared to the older\npopulation, as the younger population tends to respond well to treatment trials and their physiological conditions are stable in response to treatments. In summary, this review correlates recent\ncancer treatment strategies and the corresponding responses and survival outcomes of older and\nyounger patients.\n","PeriodicalId":11008,"journal":{"name":"Current aging science","volume":"42 6","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current aging science","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2174/0118746098241507231127114248","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
Abstract
Various developments have been observed in the treatment of cancer patients, such as
higher survival rates and better treatment outcomes. However, expecting similar outcomes in
older patients remains a challenge. The main reason for this conclusion is the exclusion of older
people from clinical trials for cancer drugs, as well as other factors, such as comorbidity, side
effects, age-related frailties and their willingness to undergo multiple treatments. However, the
discovery of new techniques and drug combinations has led to a significant improvement in the
survival of the elderly population after the onset of the disease. On the other hand, cancer treatments have not become more complex for the younger population when compared to the older
population, as the younger population tends to respond well to treatment trials and their physiological conditions are stable in response to treatments. In summary, this review correlates recent
cancer treatment strategies and the corresponding responses and survival outcomes of older and
younger patients.