tRF-1:30-Gly-CCC-3 inhibits thyroid cancer via binding to PC and modulating metabolic reprogramming

IF 3.3 2区生物学 Q1 BIOLOGY

Life Science Alliance Pub Date : 2023-12-11 DOI:10.26508/lsa.202302285

Bifei Fu, Yuming Lou, Xiaofeng Lu, Zhaolin Wu, Junjie Ni, Cong Jin, Pu Wu, Chaoyang Xu

引用次数: 0

Abstract

This study reports a mechanism of tRNA fragments in PTC whereby tRF-30 controls PC abundance and subsequent TCA cycle anaplerosis to affect metabolic reprogramming and cancer progression.

查看原文本刊更多论文

tRF-1:30-Gly-CCC-3通过与PC结合和调节代谢重编程抑制甲状腺癌

本研究报告了PTC中tRNA片段的机制，其中tRF-30控制PC丰度和随后的TCA循环逆转，从而影响代谢重编程和癌症进展。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Life Science Alliance Agricultural and Biological Sciences-Plant Science

CiteScore

5.80

自引率

2.30%

发文量

241

审稿时长

10 weeks

期刊介绍： Life Science Alliance is a global, open-access, editorially independent, and peer-reviewed journal launched by an alliance of EMBO Press, Rockefeller University Press, and Cold Spring Harbor Laboratory Press. Life Science Alliance is committed to rapid, fair, and transparent publication of valuable research from across all areas in the life sciences.