Overview of current melanoma therapies

IF 3.9 3区医学 Q2 CELL BIOLOGY

Pigment Cell & Melanoma Research Pub Date : 2023-12-08 DOI:10.1111/pcmr.13154

Anna Fateeva, Kevinn Eddy, Suzie Chen

引用次数: 0

Abstract

Melanoma is the most aggressive type of skin cancer and is responsible for the majority of deaths from skin cancer. Therapeutic advances in the last few decades, notably the development of novel targeted therapies and immunotherapies have significantly improved patient outcomes; nonetheless, these options remain limited due to the onset of resistance to treatment modalities and relapse. In this review, we focus on the available therapeutic options, their benefits, and limitations.

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当前黑色素瘤疗法概述

黑色素瘤是最具侵袭性的皮肤癌，也是造成大多数皮肤癌患者死亡的原因。过去几十年的治疗进展，特别是新型靶向疗法和免疫疗法的开发，极大地改善了患者的预后；然而，由于对治疗模式产生抗药性和复发，这些选择仍然有限。在这篇综述中，我们将重点介绍现有的治疗方案、它们的优势和局限性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Pigment Cell & Melanoma Research 医学-皮肤病学

CiteScore

8.90

自引率

2.30%

发文量

审稿时长

6-12 weeks

期刊介绍： Pigment Cell & Melanoma Researchpublishes manuscripts on all aspects of pigment cells including development, cell and molecular biology, genetics, diseases of pigment cells including melanoma. Papers that provide insights into the causes and progression of melanoma including the process of metastasis and invasion, proliferation, senescence, apoptosis or gene regulation are especially welcome, as are papers that use the melanocyte system to answer questions of general biological relevance. Papers that are purely descriptive or make only minor advances to our knowledge of pigment cells or melanoma in particular are not suitable for this journal. Keywords Pigment Cell & Melanoma Research, cell biology, melatonin, biochemistry, chemistry, comparative biology, dermatology, developmental biology, genetics, hormones, intracellular signalling, melanoma, molecular biology, ocular and extracutaneous melanin, pharmacology, photobiology, physics, pigmentary disorders