Preoperative Direct Puncture Embolization Using a Nonadhesive Ethylene Vinyl Alcohol (EVOH) Liquid Embolic Agent for Head and Neck Paragangliomas

IF 2.8 3区医学 Q2 Medicine

Clinical Neuroradiology Pub Date : 2023-12-08 DOI:10.1007/s00062-023-01364-1

Andrea M. Alexandre, Luca Scarcia, Frédéric Clarençon, Arianna Camilli, Andrea Bartolo, Francesca Incandela, Dario Antonio Mele, Mario Rigante, Marco Natola, Iacopo Valente, Francesco D’Argento, Jacopo Galli, Yamume Tshomba, Alessandro Pedicelli

{"title":"Preoperative Direct Puncture Embolization Using a Nonadhesive Ethylene Vinyl Alcohol (EVOH) Liquid Embolic Agent for Head and Neck Paragangliomas","authors":"Andrea M. Alexandre, Luca Scarcia, Frédéric Clarençon, Arianna Camilli, Andrea Bartolo, Francesca Incandela, Dario Antonio Mele, Mario Rigante, Marco Natola, Iacopo Valente, Francesco D’Argento, Jacopo Galli, Yamume Tshomba, Alessandro Pedicelli","doi":"10.1007/s00062-023-01364-1","DOIUrl":null,"url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Purpose</h3><p>This retrospective study aimed to assess the safety and technical efficacy of preoperative direct puncture embolization using a nonadhesive ethylene vinyl alcohol (EVOH) copolymer-based liquid embolic agent (LEA) combined with balloon occlusion at the origin of the external carotid artery for head and neck paragangliomas (HNP).</p><h3 data-test=\"abstract-sub-heading\">Methods</h3><p>We conducted a review of all consecutive cases of HNPs treated with direct puncture embolization using EVOH-based LEAs between 2017 and 2022 in 2 tertiary high-volume hospitals.</p><h3 data-test=\"abstract-sub-heading\">Results</h3><p>A total of 25 cases of HNPs in 24 patients underwent direct puncture embolization (12 males, 12 females, mean age 50.9 ± 15.6 years). The average lesion volume was 299.95 mm<sup>3</sup>. The mean procedure time was 139.11 min, and the mean volume of EVOHs used per case was 19.38 mL. Successful complete devascularization was achieved in all cases, with a homogeneous and deep penetration of the embolic agent into the tumor vessel bed regardless of the LEA type.</p><h3 data-test=\"abstract-sub-heading\">Conclusion</h3><p>Preoperative embolization of HNPs using a direct puncture technique and EVOHs is a safe, efficient, and feasible treatment option with a low risk of complications. This procedure facilitates surgery by transforming tumors into avascular masses that are well-delineated against the surrounding normal tissue.</p>","PeriodicalId":10391,"journal":{"name":"Clinical Neuroradiology","volume":"5 1","pages":""},"PeriodicalIF":2.8000,"publicationDate":"2023-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical Neuroradiology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s00062-023-01364-1","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"Medicine","Score":null,"Total":0}

引用次数: 0

Abstract

Purpose

This retrospective study aimed to assess the safety and technical efficacy of preoperative direct puncture embolization using a nonadhesive ethylene vinyl alcohol (EVOH) copolymer-based liquid embolic agent (LEA) combined with balloon occlusion at the origin of the external carotid artery for head and neck paragangliomas (HNP).

Methods

We conducted a review of all consecutive cases of HNPs treated with direct puncture embolization using EVOH-based LEAs between 2017 and 2022 in 2 tertiary high-volume hospitals.

Results

A total of 25 cases of HNPs in 24 patients underwent direct puncture embolization (12 males, 12 females, mean age 50.9 ± 15.6 years). The average lesion volume was 299.95 mm³. The mean procedure time was 139.11 min, and the mean volume of EVOHs used per case was 19.38 mL. Successful complete devascularization was achieved in all cases, with a homogeneous and deep penetration of the embolic agent into the tumor vessel bed regardless of the LEA type.

Conclusion

Preoperative embolization of HNPs using a direct puncture technique and EVOHs is a safe, efficient, and feasible treatment option with a low risk of complications. This procedure facilitates surgery by transforming tumors into avascular masses that are well-delineated against the surrounding normal tissue.

Abstract Image

查看原文本刊更多论文

使用非粘性乙烯-乙烯醇（EVOH）液体栓塞剂对头颈部副神经节瘤进行术前直接穿刺栓塞治疗

目的这项回顾性研究旨在评估术前使用非粘性乙烯-乙烯醇（EVOH）共聚物基液体栓塞剂（LEA）直接穿刺栓塞联合颈外动脉起源处球囊闭塞治疗头颈部副神经节瘤（HNP）的安全性和技术有效性。方法我们回顾了2017年至2022年期间在2家三甲大医院使用基于EVOH的LEA进行直接穿刺栓塞治疗的所有连续HNP病例。结果共有24名患者的25例HNP接受了直接穿刺栓塞治疗（男12例，女12例，平均年龄（50.9±15.6）岁）。平均病变体积为 299.95 立方毫米。平均手术时间为 139.11 分钟，每个病例使用的 EVOH 平均体积为 19.38 毫升。结论使用直接穿刺技术和 EVOHs 对 HNPs 进行术前栓塞是一种安全、高效、可行且并发症风险低的治疗方法。这种方法可将肿瘤转化为无血管肿块，与周围正常组织分界清晰，从而方便手术。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Clinical Neuroradiology Medicine-Radiology, Nuclear Medicine and Imaging

CiteScore

4.90

自引率

3.60%

发文量

期刊介绍： Clinical Neuroradiology provides current information, original contributions, and reviews in the field of neuroradiology. An interdisciplinary approach is accomplished by diagnostic and therapeutic contributions related to associated subjects. The international coverage and relevance of the journal is underlined by its being the official journal of the German, Swiss, and Austrian Societies of Neuroradiology.