Biomass-Derived Washable Composites for Accelerating the Healing of Infected Wounds (4/2023)

BMEMat Pub Date : 2023-12-08 DOI:10.1002/bmm2.12062
Fuhang Jiao, Wei Zhao, Wenbo Zhao, Yong Wang, Yuan Deng, Shulong Chang, Junlu Sun, Qing Lou, Lijun Wang, Chong-Xin Shan, Ying Xiao, Lin Dong
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Abstract

In this article number 10.1002/bmm2.12055, Fuhang Jiao, Wei Zhao and their co-workers developed a biomass-derived wound dressing exploiting the composite of water-soluble fish gelatin (FG) and antibacterial ZnO@silk fibroin (ZSF) microspheres. The ZSF microspheres serve as both germicide and hydrophile components, endowing the composite with excellent antimicrobial capacity and water solubility. The ZSF/FG composite can be easily removed from the wound using excess water, thereby preventing secondary damage. Additionally, the full-thickness skin wound model on infected mice demonstrated efficient wound closure and reduced inflammatory response. The ZSF/FG composite is expected a promising candidate as wound dressing for clinical therapy.

Abstract Image

用于加速感染伤口愈合的生物质可清洗复合材料 (4/2023)
在这篇编号为 10.1002/bmm2.12055 的文章中,焦富航、赵伟及其合作者利用水溶性鱼明胶(FG)和抗菌 ZnO@silk 纤维素(ZSF)微球的复合材料开发了一种生物质源伤口敷料。ZSF 微球既是杀菌剂,又是亲水成分,使复合材料具有出色的抗菌能力和水溶性。ZSF/FG 复合物可以利用多余的水轻松从伤口中清除,从而防止二次损伤。此外,在受感染小鼠的全厚皮肤伤口模型中,ZSF/FG 复合材料显示出高效的伤口闭合能力和较低的炎症反应。ZSF/FG 复合材料有望成为临床治疗中的伤口敷料。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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