Morphometric, histopathological and molecular findings of Macracanthorhynchus hirudinaceus infection in wild boar (Sus scrofa) from continental Italy

IF 2 3区农林科学 Q4 IMMUNOLOGY

Comparative Immunology Microbiology and Infectious Diseases Pub Date : 2023-12-04 DOI:10.1016/j.cimid.2023.102110

Giovanni Sgroi , Nicola D’Alessio , Antonio Varcasia , Barbara degli Uberti , Caterina Fani , Michele Trotta , Giovanna Fusco , Kandai Doi , Vincenzo Veneziano

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引用次数: 0

Abstract

Although Macracanthorhynchus hirudinaceus is a neglected acanthocephalan of suids occasionally responsible for severe infections in humans, the spread of wild boar (Sus scrofa) populations in Europe could promote the circulation. Herein, we report the first morphometric, histological and molecular characterization of a severe M. hirudinaceus infection in a boar from continental Italy. The boar’s intestine displayed granulomatous enteritis due to 24 helminths (14 females, 10 males), identified as adults of M. hirudinaceus by a combined morphometric/molecular approach. The phylogenetic analysis of the cox1 gene revealed a close relationship of the M. hirudinaceus sequence type found herein with those from Hungary and insular Italy. The high haplotype diversity and low nucleotide diversity of M. hirudinaceus specimens would suggest its rapid demographic expansion in the Mediterranean basin. More research is needed to assess the presence of M. hirudinaceus in susceptible beetle species and the role of boars in the epidemiology of infection.

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意大利大陆野猪水蛭Macracanthorhynchus感染的形态学、组织病理学和分子特征

尽管Macracanthorhynchus hirudinaceus是一种被忽视的棘头类猪，偶尔会引起人类的严重感染，但野猪(Sus scrofa)种群在欧洲的传播可以促进这种循环。在此，我们报告了意大利大陆一头公猪严重水蛭分枝杆菌感染的第一个形态计量学、组织学和分子特征。猪肠显示肉芽肿性肠炎，由24个蠕虫(14个雌性，10个雄性)引起，通过形态计量学/分子联合方法确定为水蛭绦虫的成虫。cox1基因的系统发育分析表明，在这里发现的M. hirudinaceus序列类型与匈牙利和意大利岛的序列类型有密切的关系。高单倍型多样性和低核苷酸多样性表明其在地中海盆地的快速人口扩张。需要更多的研究来评估水蛭杆菌在易感甲虫物种中的存在以及公猪在感染流行病学中的作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Comparative Immunology Microbiology and Infectious Diseases 医学-免疫学

CiteScore

4.60

自引率

0.00%

发文量

102

审稿时长

40 days

期刊介绍： Comparative Immunology, Microbiology & Infectious Diseases aims to respond to the concept of "One Medicine" and to provide a venue for scientific exchange. Based on the concept of "Comparative Medicine" interdisciplinary cooperation between specialists in human and animal medicine is of mutual interest and benefit. Therefore, there is need to combine the respective interest of physicians, veterinarians and other health professionals for comparative studies relevant to either human or animal medicine . The journal is open to subjects of common interest related to the immunology, immunopathology, microbiology, parasitology and epidemiology of human and animal infectious diseases, especially zoonotic infections, and animal models of human infectious diseases. The role of environmental factors in disease emergence is emphasized. CIMID is mainly focusing on applied veterinary and human medicine rather than on fundamental experimental research.