Detection of Infected and Normal Blood Sample Containing Plasma Using Long-Range Surface Plasmon Resonance Sensor

IF 3.3 4区物理与天体物理 Q2 CHEMISTRY, PHYSICAL

Plasmonics Pub Date : 2023-11-25 DOI:10.1007/s11468-023-02121-3

Saravanan Pandiaraj, Muthumareeswaran Muthuramamoorthy, Nadyah Alanazi, Abdullah N. Alodhayb

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Abstract

A long-range surface plasmon biosensor (LRSPR) using the 2S2G/Teflon/Au MXene/Sensing medium (SM) is proposed for improve the imaging sensitivity. Here, the MXene layer is used to improve imaging sensitivity and protect against unwanted oxidation of Au layer. MXene having formula is Ti₃C₂Tx layered materials with hydrophilic nature, better stability, good conductivity and large surface area. The proposed LRSPR uses the high adsorption efficiency and high resolution. Numerically investigate the imaging sensitivity compared to the conventional surface plasmon sensor (cSPR) as well as systematic layer of proposed LRSPR sensor. The maximum imaging sensitivity of 10,465/RIU at 1.35 based RI of plasma sensing medium is achieved. The maximum electric field normalized at the interface between the Teflon-Au layer in the proposed sensor and the Au/MXene layer in the cSPR sensor. For the proposed LRSPR sensor, the penetration depth (PD) of the field into the sensing medium of 611.7 nm and 806.13 nm is obtained at Au-SM and MXene-SM interface for the sensing medium of 1.337 and 1.350. In addition, the figure of merit (FoM) as 193/RIU and 275.6/RIU is exhibited for the same sensing medium.

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用远程表面等离子体共振传感器检测含血浆的感染和正常血样

为了提高成像灵敏度，提出了一种采用2S2G/Teflon/Au MXene/传感介质(SM)的远程表面等离子体生物传感器(LRSPR)。在这里，MXene层用于提高成像灵敏度并防止Au层的不必要氧化。MXene的分子式是Ti3C2Tx层状材料，具有亲水性，稳定性好，导电性好，表面积大。LRSPR具有高吸附效率和高分辨率的特点。数值研究了与传统表面等离子体传感器(cSPR)相比的成像灵敏度以及所提出的LRSPR传感器的系统层。在基于1.35的等离子体感测介质中，达到了10465 /RIU的最大成像灵敏度。该传感器中Teflon-Au层与cSPR传感器中Au/MXene层之间的界面处归一化的最大电场。对于所提出的LRSPR传感器，在Au-SM和MXene-SM界面处，感应介质为1.337和1.350时，获得了磁场对感应介质的穿透深度(PD)分别为611.7 nm和806.13 nm。此外，对于相同的传感介质，性能值(FoM)分别为193/RIU和275.6/RIU。

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来源期刊

Plasmonics 工程技术-材料科学：综合

CiteScore

5.90

自引率

6.70%

发文量

164

审稿时长

2.1 months

期刊介绍： Plasmonics is an international forum for the publication of peer-reviewed leading-edge original articles that both advance and report our knowledge base and practice of the interactions of free-metal electrons, Plasmons. Topics covered include notable advances in the theory, Physics, and applications of surface plasmons in metals, to the rapidly emerging areas of nanotechnology, biophotonics, sensing, biochemistry and medicine. Topics, including the theory, synthesis and optical properties of noble metal nanostructures, patterned surfaces or materials, continuous or grated surfaces, devices, or wires for their multifarious applications are particularly welcome. Typical applications might include but are not limited to, surface enhanced spectroscopic properties, such as Raman scattering or fluorescence, as well developments in techniques such as surface plasmon resonance and near-field scanning optical microscopy.