Secondary Metabolites of Bifido- and Lactobacteria Fulfilling Signal Functions

IF 1.3 4区生物学 Q4 MICROBIOLOGY

Microbiology Pub Date : 2023-11-28 DOI:10.1134/s0026261723601549

O. V. Bukharin, N. B. Perunova, Yu. A. Nikolaev, E. V. Ivanova, A. V. Oleskin, G. I. El’-Registan

引用次数: 0

Abstract

The culture liquid of lactic-acid bacteria (LABs) and bifidobacteria contained secondary metabolites fulfilling signal functions, such as guaiacol and γ-butyrolactone. In addition, 4-hexylresorcinol was detected in the cell extract of Bifidobacterium bifidum 791. No homoserine lactones were produced by the tested microorganisms. The presence of metabolites with signal functions in conjunction with the available data on the synthesis of neuroactive amines, amino acids, and prebiotics by LABs and bifidobacteria indicates that these bacteria can strongly influence the functioning of the whole human symbiotic microbiota as well as the human host’s health state.

查看原文本刊更多论文

双歧杆菌和乳杆菌完成信号功能的次生代谢物

摘要乳酸菌和双歧杆菌培养液中含有愈创木酚和γ-丁内酯等具有信号功能的次生代谢产物。此外，在两歧双歧杆菌791细胞提取物中检测到4-己基间苯二酚。所测微生物不产生同型丝氨酸内酯。具有信号功能的代谢物的存在，结合实验室和双歧杆菌合成神经活性胺、氨基酸和益生元的现有数据，表明这些细菌可以强烈影响整个人类共生微生物群的功能以及人类宿主的健康状态。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Microbiology 生物-微生物学

CiteScore

2.40

自引率

13.30%

发文量

审稿时长

6-12 weeks

期刊介绍： Microbiology is an is an international peer reviewed journal that covers a wide range of problems in the areas of fundamental and applied microbiology. The journal publishes experimental and theoretical papers, reviews on modern trends in different fields of microbiological science, and short communications with descriptions of unusual observations. The journal welcomes manuscripts from all countries in the English or Russian language.