Facile Synthesis of Spiro[cyclohexane-1,3’-indoline]-2,2’-diones

IF 1.3 3区化学 Q3 CHEMISTRY, ORGANIC

Heterocyclic Communications Pub Date : 2019-12-31 DOI:10.1515/hc-2019-0022

Shin-taro Katayama, Hiroshi Nishino

引用次数: 1

Abstract

Abstract Spiro[cyclohexane-1,3’-indoline]-2,2’-diones were easily prepared in good to high yields by the oxidation of N-aryl-N-methyl-2-oxocyclohexane-1-carboxamides in one pot with a short reaction time. The spiroindolinediones could be important for the total synthesis of natural products.

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螺旋[环己烷-1,3 ' -吲哚]-2,2 ' -二酮的简易合成

摘要利用n -芳基- n -甲基-2-氧环己烷-1-羧酰胺在一锅内氧化制备了螺[环己烷-1,3 ' -吲哚]-2,2 ' -二酮，反应时间短，产率高。螺哚啉酮类化合物对天然产物的全合成具有重要意义。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Heterocyclic Communications 化学-有机化学

CiteScore

3.80

自引率

4.30%

发文量

审稿时长

1.4 months

期刊介绍： Heterocyclic Communications (HC) is a bimonthly, peer-reviewed journal publishing preliminary communications, research articles, and reviews on significant developments in all phases of heterocyclic chemistry, including general synthesis, natural products, computational analysis, considerable biological activity and inorganic ring systems. Clear presentation of experimental and computational data is strongly emphasized. Heterocyclic chemistry is a rapidly growing field. By some estimates original research papers in heterocyclic chemistry have increased to more than 60% of the current organic chemistry literature published. This explosive growth is even greater when considering heterocyclic research published in materials science, physical, biophysical, analytical, bioorganic, pharmaceutical, medicinal and natural products journals. There is a need, therefore, for a journal dedicated explicitly to heterocyclic chemistry and the properties of heterocyclic compounds.