Heyue Huang, Chuanpei Xu, Peng Long, Yanzhang Chen, Xijun Huang, Zheng Liu, Hong Yang
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引用次数: 0
Abstract
Structures of paper-based microfluidic chips affect the sweat-absorbing time when they are used for sweat analysis. For the first time, we use COMSOL to establish two types of paper-based chip sweat-absorbing models that can quantitatively analyze this phenomenon. The standard model contains 1089 sweat glands, and the simplified model simplifies it according to the idea of finite element division, including 81 sweat glands. Sweat flows in from the bottom of the paper-based chip and out from the electrode contact surface (the upper surface of the central cylinder of the paper-based chip). Both models contain six paper-based chip structures, use Richards’ equation as the governing equation, set the outflow velocity to 0, and set the sweating rate of a sweat gland at 0.6 \(\mu\)L/min. In the standard model, it takes only 46 s for the paper-based structure with the fastest sweat-absorbing speed to completely saturate the electrode contact surface with sweat (meaning the sweat-absorbing time is 46 s), which is 13.06\(\%\) shorter than that of the slowest structure. In the simplified model, the top 3 structures of sweat-absorbing speed are consistent with the standard model. The simulation results show that the sweat-absorbing time is positively correlated with the H value of the bottom surface of the paper-based structure (defined as the area of the bottom surface /the area of sweat glands covered by the bottom surface), which can be proved by analytical and experimental methods. The analytical method proves that this conclusion can be generalized to other sweating rate conditions.
期刊介绍:
Microfluidics and Nanofluidics is an international peer-reviewed journal that aims to publish papers in all aspects of microfluidics, nanofluidics and lab-on-a-chip science and technology. The objectives of the journal are to (1) provide an overview of the current state of the research and development in microfluidics, nanofluidics and lab-on-a-chip devices, (2) improve the fundamental understanding of microfluidic and nanofluidic phenomena, and (3) discuss applications of microfluidics, nanofluidics and lab-on-a-chip devices. Topics covered in this journal include:
1.000 Fundamental principles of micro- and nanoscale phenomena like,
flow, mass transport and reactions
3.000 Theoretical models and numerical simulation with experimental and/or analytical proof
4.000 Novel measurement & characterization technologies
5.000 Devices (actuators and sensors)
6.000 New unit-operations for dedicated microfluidic platforms
7.000 Lab-on-a-Chip applications
8.000 Microfabrication technologies and materials
Please note, Microfluidics and Nanofluidics does not publish manuscripts studying pure microscale heat transfer since there are many journals that cover this field of research (Journal of Heat Transfer, Journal of Heat and Mass Transfer, Journal of Heat and Fluid Flow, etc.).