{"title":"Micropattern-Based Stem Cell Gym: Mechanical Memory Enhanced Stemness Maintenance of Human Dental Pulp Stem Cells and Nerve Regeneration (Adv. Funct. Mater. 49/2023)","authors":"Chiyu Li, Fanqi Meng, Zhijie Yang, Jiang Peng, Yuwei Guo, Jing Na, Qiusheng Shi, Yu Liu, Yu Wang, Lisha Zheng, Yubo Fan","doi":"10.1002/adfm.202370292","DOIUrl":null,"url":null,"abstract":"<p><b>Stem Cell Gym</b></p><p>In article number 2302829, Yu Wang, Lisha Zheng, Yubo Fan, and co-workers develop a micropatterned based stem cell gym to train dental pulp stem cells for stemness maintenance. The micropattern based gym with 1024 μm<sup>2</sup> and aspect ratios of 1:2 and 1:4 effectively enhances the stemness and rescues the pluripotency of stem cells during long-term expansion. The stem cell gym-induced mechanical memory also promotes nerve regeneration in vivo.\n\n <figure>\n <div><picture>\n <source></source></picture><p></p>\n </div>\n </figure></p>","PeriodicalId":112,"journal":{"name":"Advanced Functional Materials","volume":"33 49","pages":""},"PeriodicalIF":18.5000,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/adfm.202370292","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Advanced Functional Materials","FirstCategoryId":"88","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/adfm.202370292","RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0
Abstract
Stem Cell Gym
In article number 2302829, Yu Wang, Lisha Zheng, Yubo Fan, and co-workers develop a micropatterned based stem cell gym to train dental pulp stem cells for stemness maintenance. The micropattern based gym with 1024 μm2 and aspect ratios of 1:2 and 1:4 effectively enhances the stemness and rescues the pluripotency of stem cells during long-term expansion. The stem cell gym-induced mechanical memory also promotes nerve regeneration in vivo.
期刊介绍:
Firmly established as a top-tier materials science journal, Advanced Functional Materials reports breakthrough research in all aspects of materials science, including nanotechnology, chemistry, physics, and biology every week.
Advanced Functional Materials is known for its rapid and fair peer review, quality content, and high impact, making it the first choice of the international materials science community.