Opportunities and challenges for deep learning in cell dynamics research.

IF 13 1区 生物学 Q1 CELL BIOLOGY
Trends in Cell Biology Pub Date : 2024-11-01 Epub Date: 2023-11-28 DOI:10.1016/j.tcb.2023.10.010
Binghao Chai, Christoforos Efstathiou, Haoran Yue, Viji M Draviam
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引用次数: 0

Abstract

The growth of artificial intelligence (AI) has led to an increase in the adoption of computer vision and deep learning (DL) techniques for the evaluation of microscopy images and movies. This adoption has not only addressed hurdles in quantitative analysis of dynamic cell biological processes but has also started to support advances in drug development, precision medicine, and genome-phenome mapping. We survey existing AI-based techniques and tools, as well as open-source datasets, with a specific focus on the computational tasks of segmentation, classification, and tracking of cellular and subcellular structures and dynamics. We summarise long-standing challenges in microscopy video analysis from a computational perspective and review emerging research frontiers and innovative applications for DL-guided automation in cell dynamics research.

细胞动力学研究中深度学习的机遇与挑战。
人工智能(AI)的发展导致越来越多地采用计算机视觉和深度学习(DL)技术来评估显微镜图像和电影。这种采用不仅解决了动态细胞生物学过程定量分析的障碍,而且开始支持药物开发、精准医学和基因组-表型图谱绘制的进步。我们调查了现有的基于人工智能的技术和工具,以及开源数据集,特别关注细胞和亚细胞结构和动态的分割,分类和跟踪的计算任务。我们从计算的角度总结了显微镜视频分析的长期挑战,并回顾了细胞动力学研究中dl引导自动化的新兴研究前沿和创新应用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Trends in Cell Biology
Trends in Cell Biology 生物-细胞生物学
CiteScore
32.00
自引率
0.50%
发文量
160
审稿时长
61 days
期刊介绍: Trends in Cell Biology stands as a prominent review journal in molecular and cell biology. Monthly review articles track the current breadth and depth of research in cell biology, reporting on emerging developments and integrating various methods, disciplines, and principles. Beyond Reviews, the journal features Opinion articles that follow trends, offer innovative ideas, and provide insights into the implications of new developments, suggesting future directions. All articles are commissioned from leading scientists and undergo rigorous peer-review to ensure balance and accuracy.
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