Short-term outcomes of pancreatoduodenectomy in older individuals over a 9-year period using real-world data: A multilevel analysis based on a nationwide administrative database in Japan

IF 3.2 3区医学 Q2 GASTROENTEROLOGY & HEPATOLOGY

Journal of Hepato‐Biliary‐Pancreatic Sciences Pub Date : 2023-11-30 DOI:10.1002/jhbp.1396

Yasuhisa Mori, Makoto Okawara, Kazunori Shibao, Shiro Kohi, Toshihisa Tamura, Norihiro Sato, Yoshihisa Fujino, Kiyohide Fushimi, Shinya Matsuda, Keiji Hirata

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引用次数: 0

Abstract

Background

We aimed to evaluate the short-term outcomes of pancreatoduodenectomy (PD) in older individuals.

Methods

Data from the Japanese Diagnosis Procedure Combination database on 62 275 patients who underwent PD from 1 April 2012 to 31 March 2020 were analyzed. Patients were divided into five age groups: <70, 70–74, 75–79, 80–84, and ≥85 years. The associations between postoperative outcomes and age were investigated using multilevel analysis. The mean differences in length of hospital stay and cost were also compared.

Results

The rate of PD in older individuals increased annually. Compared with the youngest age group (< 70 years), the incidence rate ratios for in-hospital mortality were 1.52 (95% confidence interval [CI]: 1.30–1.76), 2.07 (1.82–2.37), 2.29 (1.94–2.71), and 2.92 (2.20–3.87) in the 70–74, 75–79, 80–84, and ≥ 85-year-old age groups, respectively (all p < .001). Postoperative complications, length of postoperative hospital stay, and cost increased significantly with increasing age.

Conclusions

These real-world data emphasize the higher levels of morbidity, mortality, and cost in older patients. Careful attention should be paid when considering the indication for PD in older individuals.

Abstract Image

查看原文本刊更多论文

使用真实世界数据的9年老年人胰十二指肠切除术的短期结果:基于日本全国行政数据库的多层次分析。

背景:我们旨在评估老年人胰十二指肠切除术(PD)的短期预后。方法:分析2012年4月1日至2020年3月31日日本诊断程序组合数据库中62 275例PD患者的数据。将患者分为5个年龄组:结果:老年个体PD发病率逐年上升。结论:这些真实世界的数据强调老年患者的发病率、死亡率和成本水平更高。在考虑老年个体PD的适应症时应多加注意。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Hepato‐Biliary‐Pancreatic Sciences GASTROENTEROLOGY & HEPATOLOGY-SURGERY

自引率

10.00%

发文量

178

审稿时长

6-12 weeks

期刊介绍： The Journal of Hepato-Biliary-Pancreatic Sciences (JHBPS) is the leading peer-reviewed journal in the field of hepato-biliary-pancreatic sciences. JHBPS publishes articles dealing with clinical research as well as translational research on all aspects of this field. Coverage includes Original Article, Review Article, Images of Interest, Rapid Communication and an announcement section. Letters to the Editor and comments on the journal’s policies or content are also included. JHBPS welcomes submissions from surgeons, physicians, endoscopists, radiologists, oncologists, and pathologists.