Efficacy of topical curcuma longa in the healing of extraction sockets: A split-mouth clinical trial.

Q2 Dentistry
Dental Research Journal Pub Date : 2023-10-26 eCollection Date: 2023-01-01
Kalpa Pandya, Devee Abbinayah, Deepshika Selvakumar, Naveen Jayakumar
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Abstract

Background: The healing process after dental extraction is influenced by various factors, and finding effective strategies for promoting wound healing and reducing postoperative discomfort remains a challenge. This study aimed to evaluate the effectiveness of topical Curcuma longa gel in reducing pain and promoting wound healing after dental extraction, with the secondary objective of assessing the occurrence of dry sockets. The study was a split-mouth randomized controlled trial conducted at the oral and maxillofacial surgery department over 3 months.

Materials and methods: This split-mouth randomized controlled trial consisted of a total of 21 patients undergoing bilateral extractions. One extraction socket was randomly assigned to the test group, where Curcuma. longa gel was applied, while the contralateral socket served as the control group, receiving a placebo. Pain and wound healing were evaluated using standardized scales on the 3rd and 7th days postextraction. Descriptive statistics, paired t-tests, and unpaired t-tests were performed using the SPSS software version 19. The statistical significance was fixed at P ≤ 0.05.

Results: The test group showed significantly higher mean healing scores on the 3rd and 7th days compared to the control group. On the 7th day, the test group had significantly lower mean pain scores than the control group. No cases of dry sockets were observed in either group.

Conclusion: Topical Curcuma longa gel demonstrated positive effects in promoting wound healing and reducing pain after dental extraction. Clinicians should consider the use of Curcuma longa gel as a post-extraction medicament, particularly in cases involving multiple or traumatic extractions.

局部姜黄对拔牙槽愈合的疗效:一项裂口临床试验。
背景:拔牙后的愈合过程受到多种因素的影响,寻找促进创面愈合和减少术后不适的有效策略仍然是一个挑战。本研究旨在评估局部姜黄凝胶在拔牙后减轻疼痛和促进伤口愈合的有效性,次要目的是评估干牙槽的发生情况。本研究是在口腔颌面外科进行的一项为期3个月的裂口随机对照试验。材料与方法:本试验采用裂口法随机对照,共21例患者行双侧拔牙。一个提取槽随机分配给试验组,其中姜黄。应用Longa凝胶,而对侧窝作为对照组,接受安慰剂。拔牙后第3天和第7天采用标准化量表评估疼痛和伤口愈合情况。使用SPSS软件19进行描述性统计、配对t检验和非配对t检验。差异有统计学意义,P≤0.05。结果:实验组在第3、7天的平均愈合评分明显高于对照组。第7天,实验组的平均疼痛评分明显低于对照组。两组均未见干窝病例。结论:姜黄凝胶具有促进拔牙术后创面愈合、减轻疼痛的积极作用。临床医生应该考虑使用姜黄凝胶作为提取后的药物,特别是在涉及多次或创伤性提取的情况下。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Dental Research Journal
Dental Research Journal Dentistry-Dentistry (all)
CiteScore
1.70
自引率
0.00%
发文量
70
审稿时长
52 weeks
期刊介绍: Dental Research Journal, a publication of Isfahan University of Medical Sciences, is a peer-reviewed online journal with Bimonthly print on demand compilation of issues published. The journal’s full text is available online at http://www.drjjournal.net. The journal allows free access (Open Access) to its contents and permits authors to self-archive final accepted version of the articles on any OAI-compliant institutional / subject-based repository. The journal will cover technical and clinical studies related to health, ethical and social issues in field of Dentistry. Articles with clinical interest and implications will be given preference.
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