The outcome of heart failure in women: a study from a tertiary heart function clinic.

IF 1.3
American journal of cardiovascular disease Pub Date : 2023-10-15 eCollection Date: 2023-01-01
Abeer Bakhsh, Alaa AlSayed, Mohammed AlTamimi, Raneem Alodhaib, Munira Binhudhud, Hadeel Ghazal, Yahya Al Hebaishi
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Abstract

Background: Women have unique risk factors for heart disease and a higher risk of cardiovascular mortality. Heart failure (HF) prevalence in women is affected by age, pregnancy, and menopause. More understanding of HF etiology, management, and outcome in women is needed.

Method: a retrospective study of women diagnosed with HF following at a heart function clinic (HFC) in a tertiary cardiac center.

Results: A total of 1988 HF patients were screened. Women accounted for 561 (28.2%). The mean age at first HF presentation was 47.7 ± 17.9 years. The most common diagnosis was HF with reduced ejection fraction (HFrEF ≤ 40%) 473 (84%). The most frequent cause of HF was dilated cardiomyopathy (DCM) in 304 patients (54.2%). Prevalence of diabetes (DM) was 272 (48.5%), hypertension (HTN) 267 (47.6%), and body mass index (BMI) ≥ 30 was 332 (59%). Adverse pregnancy events included miscarriages 151 (38.6%), preeclampsia 15 (3.8%), and spontaneous coronary dissection 3 (0.8%). Left ventricle recovery to EF ≥ 50% occurred in 116 (20.7%) patients, while death occurred in 32 (5.7%) patients during follow-up. Women living with chronic HF were 240 (42.8%). The use of beta-blockers occurred in (96%), renin-angiotensin enzyme inhibitors (86.6%), mineralocorticoids (55.4%), and sodium-glucose cotransporter 2 inhibitors (31.6%). Women who had a heart transplant were 19 (3.75%).

Conclusion: Referral to specialized heart function clinics remains low for women. There is high burden of obesity among women and the majority of women have chronic HF but advanced HF therapy consideration is low in women.

妇女心力衰竭的结果:来自三级心功能诊所的研究。
背景:女性有独特的心脏病危险因素和较高的心血管死亡风险。女性心力衰竭(HF)患病率受年龄、妊娠和绝经期的影响。需要更多地了解女性心衰的病因、管理和结果。方法:对在三级心脏中心心功能诊所(HFC)诊断为HF的妇女进行回顾性研究。结果:共筛查HF患者1988例。女性占561人(28.2%)。首次出现HF的平均年龄为47.7±17.9岁。最常见的诊断是HF伴射血分数降低(HFrEF≤40%)473(84%)。304例患者中最常见的心肌病是扩张型心肌病(DCM)(54.2%)。糖尿病(DM) 272例(48.5%),高血压(HTN) 267例(47.6%),体重指数(BMI)≥30为332例(59%)。不良妊娠事件包括流产151例(38.6%),先兆子痫15例(3.8%),自发性冠状动脉夹层3例(0.8%)。随访期间,116例(20.7%)患者左心室恢复至EF≥50%,32例(5.7%)患者死亡。患有慢性心衰的女性为240人(42.8%)。β受体阻滞剂(96%)、肾素-血管紧张素酶抑制剂(86.6%)、矿糖皮质激素(55.4%)和钠-葡萄糖共转运蛋白2抑制剂(31.6%)的患者使用β受体阻滞剂。接受心脏移植的女性19例(3.75%)。结论:转诊到专门的心脏功能诊所的妇女仍然很低。妇女肥胖负担高,大多数妇女患有慢性心衰,但妇女对晚期心衰治疗的考虑较少。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
American journal of cardiovascular disease
American journal of cardiovascular disease CARDIAC & CARDIOVASCULAR SYSTEMS-
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