A 12-Year Comparison of Alzheimer's Dementia Patients With Their Informants in Taiwan.

American journal of Alzheimer's disease and other dementias Pub Date : 2023-01-01 DOI:10.1177/15333175231218089

Kai-Ming Jhang, Wen-Fu Wang, Kuang-Nan Hsu, Shang-Chien Huang, Sheng-Hsiang Yang, Ling-Chun Huang, Yuan-Han Yang

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Abstract

Background: To update the characteristics of patients with Alzheimer's disease (AD) and their informants in Taiwan and compare them from 12 years ago.

Methods: 1218 patients with AD and their informants were recruited from six hospitals in Taiwan. The uniform data set version 3.0 (UDS3, form A1-A3) were administered.

Results: Compared with the first registration from 2010-2012 (n = 691), the mean clinical dementia rating sum of boxes score was significantly lower, more patients living independently, and more informants not living together with the patients. A total of 11.2%, 4.1%, 12.8%, and 0.5% of the patients had a reported history of cognitive impairment in their mothers, fathers, siblings, and children, respectively.

Conclusion: Compared with the data from 2010, patients have been diagnosed at a milder disease stage, and their informants used telephone contact more frequently instead of living with the patients. Family histories of cognitive impairment in patients with AD remain frequent.

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台湾阿尔茨海默氏痴呆患者与被告知者的12年比较。

背景:更新台湾阿尔茨海默病(AD)患者及其举报人的特征，并与12年前进行比较。方法:从台湾6家医院招募1218例AD患者及其举报人。采用统一数据集3.0版本(UDS3，表格A1-A3)。结果:与首次登记的2010-2012年(n = 691)相比，临床痴呆的box评分和平均值显著降低，独立生活的患者增多，不与患者一起生活的举报者增多。分别有11.2%、4.1%、12.8%和0.5%的患者报告其母亲、父亲、兄弟姐妹和子女有认知障碍史。结论:与2010年的数据相比，患者的诊断处于较轻的疾病阶段，其举报人使用电话联系的频率增加，而不是与患者一起生活。阿尔茨海默病患者的认知障碍家族史仍然很常见。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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American journal of Alzheimer's disease and other dementias

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