Health-related quality of life is improved after coronary artery bypass graft surgery: a 1-year follow-up study.

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2023-12-01 Epub Date: 2023-11-27 DOI:10.1080/14017431.2023.2284083

Laura Hämäläinen, Mika Kohonen, Jari Laurikka

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引用次数: 0

Abstract

Objectives: The purpose of this study was to detect changes in QoL after coronary artery bypass grafting surgeries (CABG) in one year, and to identify the possible predictive factors associated with the change.

Design: A single-center prospective study of 501 patients was conducted between 2013 and 2018 using the EQ-5D VAS questionnaire for estimating the QoL. The patients filled in a questionnaire preoperatively, at 6 and at 12 months postoperatively. Univariate and multivariable logistic regression analyses were used to find out if certain pre-selected factors or EQ5D dimensions had independent effects on the observed EQ VAS scores.

Results: QoL improved in all EQ-5D dimensions and in EQ VAS scores at 6 and at 12 months: the greatest changes in the number of reported problems were in the dimensions "mobility" (-34.2%, p<.001), "self-care" (-36.7%, p=.001) and "pain or discomfort" (-31.0%, p<.001). With the multivariable regression model, we could show that normal left ventricle ejection fraction (LVEF) and improvement in mobility and pain/discomfort dimensions were in association with improvement of EQ VAS score at 6 months. At 12 months this association was no longer detectable.

Conclusions: CABG procedure can improve patient's QoL when judged with EQ5D dimensions and related overall self-rated health (VAS). This improvement was seen both at 6 and at 12 months postoperatively. Except for LVEF, the other patient-specific risk factors we examined did not seem to affect QoL in the long term.

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冠状动脉搭桥术后健康相关生活质量改善:1年随访研究

目的:本研究的目的是检测冠状动脉旁路移植术(CABG)术后一年内生活质量的变化，并确定可能与这种变化相关的预测因素。设计:2013年至2018年间，采用EQ-5D VAS问卷评估生活质量，对501例患者进行单中心前瞻性研究。患者术前、术后6个月和12个月分别填写问卷。采用单变量和多变量logistic回归分析，确定某些预选因素或EQ5D维度是否对观察到的EQ VAS评分有独立影响。结果:6个月和12个月时EQ- 5d各维度和EQ VAS评分的生活质量均有改善，报告问题数量变化最大的是“活动能力”维度(-34.2%，pp=.001)和“疼痛或不适”维度(-31.0%，p)。结论:以EQ5D维度和相关的整体自评健康(VAS)来判断CABG手术可改善患者的生活质量。这种改善在术后6个月和12个月均可观察到。除LVEF外，我们检查的其他患者特异性风险因素似乎并不影响长期生活质量。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.