Safety and feasibility of pulmonary rehabilitation in patients hospitalized with post-COVID-19 fibrosis: A feasibility study.

IF 2.2 4区医学 Q1 REHABILITATION

PM&R Pub Date : 2024-08-01 Epub Date: 2024-01-18 DOI:10.1002/pmrj.13113

Shruti P Nair, Anulucia Augustine, Chaitrali Panchabhai, Sarika Patil, Kinjal Parmar, Vrushali P Panhale

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引用次数: 0

Abstract

Background: Emerging data suggest a spectrum of pulmonary complications from COVID-19, ranging from dyspnea to difficult ventilator weaning and fibrotic lung damage. Prolonged hospitalization is known to significantly affect activity levels, impair muscle strength and reduce cardiopulmonary endurance.

Objective: To assess the feasibility and safety of inpatient pulmonary rehabilitation (PR) and to explore effects on functional capacity, physical performance, fatigue levels, and functional status.

Design: A prospective feasibility study.

Setting: Inpatient unit of a tertiary care hospital.

Participants: Twenty-five hospitalized patients diagnosed with post-COVID-19 fibrosis referred for PR.

Intervention: Individualized PR intervention including breathing exercises, positioning, strengthening, functional training, and ambulation twice a day for 6 days a week.

Outcome measures: One-minute sit-to-stand test (STST), Short Physical Performance Battery (SPPB), Fatigue Assessment Scale (FAS), and Post-COVID-19 Functional Status Scale (PCFS).

Results: Twenty-five participants (19 males, 6 females) with a mean age of 54.2 ± 13.4 years were enrolled. Sixteen completed the two-point assessment after undergoing in-patient PR of mean duration 14.8 ± 9 days. PR led to a significant improvement in all functional outcomes that is, STST (from 7.1 ± 4.3 repetitions to 14.2 ± 2.1 repetitions, SPPB (from 5 ± 2.8 to 9.4 ± 1.5), FAS (from 33.3 ± 10.8 to 25.8 ± 4.7) at the p ≤ .001, and PCFS (from 3.6 ± 0.9 to 2.9 ± 1.2, p ≤ .05).

Conclusion: Early initiation of PR for hospitalized patients with COVID-19 fibrosis was safe, well tolerated, and feasible and may improve functional status.

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肺炎后纤维化住院患者肺康复的安全性和可行性:一项可行性研究

背景:新出现的数据表明，COVID-19存在一系列肺部并发症，从呼吸困难到难以脱下呼吸机和纤维化肺损伤。已知长期住院会显著影响活动水平，损害肌肉力量并降低心肺耐力。目的:评价住院肺康复(PR)的可行性和安全性，探讨其对功能能力、体能、疲劳水平和功能状态的影响。设计:前瞻性可行性研究。环境:三级护理医院的住院病房。参与者:25例诊断为covid -19后纤维化的住院患者转介肺部康复(PR)。干预:个体化公关干预，包括呼吸练习、定位、强化、功能训练和步行，每天两次，每周六天。结果测量:1分钟坐立测试(STST)、短时间物理性能电池(SPPB)、疲劳评估量表(FAS)和covid -19后功能状态量表(PCFS)。结果:纳入25例受试者(男19例，女6例)，平均年龄54.25±13.36岁。16例患者在住院PR(平均14.8±9天)后完成2点评估。PR可显著改善所有功能指标，即STST(从7.1±4.3次重复到14.2±2.1次重复)、SPPB(从5±2.8次重复到9.4±1.5次重复)、FAS(从33.3±10.8到25.8±4.7次重复)(p值≤0.001)和PCFS(从3.6±0.9到2.9±1.2次重复，p值≤0.05)。结论:住院COVID-19纤维化患者早期开始PR是安全、耐受性好、可行的，可改善功能状态。这篇文章受版权保护。版权所有。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

PM&R REHABILITATION-SPORT SCIENCES

CiteScore

4.30

自引率

4.80%

发文量

187

审稿时长

4-8 weeks

期刊介绍： Topics covered include acute and chronic musculoskeletal disorders and pain, neurologic conditions involving the central and peripheral nervous systems, rehabilitation of impairments associated with disabilities in adults and children, and neurophysiology and electrodiagnosis. PM&R emphasizes principles of injury, function, and rehabilitation, and is designed to be relevant to practitioners and researchers in a variety of medical and surgical specialties and rehabilitation disciplines including allied health.