Chemical composition and biological evaluation of the essential oil of the flowering aerial parts of Aegopodium alpestre Ledeb

IF 1.9 3区化学 Q3 CHEMISTRY, APPLIED

Natural Product Research Pub Date : 2025-02-16 DOI:10.1080/14786419.2023.2286605

Aijiao Zhong , Peng Shen , Yue Sun , Jiaxin Feng , Junyi Zhu , Li Li , Zijing Wu , Hao Zang

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Abstract

Aegopodium alpestre Ledeb (A. alpestre) is a plant known for its fragrant smell and has been traditionally used to treat influenza. However, despite its widespread use, there is no research on its flowering aerial parts. This study aims to contribute to the understanding the flowering aerial parts by investigating its volatile oil. The essential oil was extracted through hydrodistillation and analysed using GC-MS. The analysis identified 54 compounds, which accounted for 95.16% of the oil composition. The major components are germacrene D (31.68%), β-caryophyllene (16.07%), and (E)-β-farnesene (7.99%). To evaluate the antioxidant activity of volatile oil, six antioxidant experiments were conducted. The results indicated that volatile oil exhibited significant 2,2’-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) diammonium salt and hydroxyl radical scavenging abilities. Furthermore, the antibacterial activity of volatile oil was assessed against four common pathogenic bacteria. The findings demonstrated that volatile oil displayed potent antibacterial activity against Escherichia coli and Aerogenic bacterium.

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海棠地上开花部位精油的化学成分及生物学评价。

海豆蔻(a. alpestre)是一种以其芳香气味而闻名的植物，传统上用于治疗流感。然而，尽管它被广泛使用，但没有对其开花的空中部分进行研究。本研究旨在通过对其挥发油的研究，为了解开花的地上部分做出贡献。采用水蒸气蒸馏法提取精油，气相色谱-质谱联用分析。分析鉴定出54种化合物，占油成分的95.16%。主要成分为绿蜡烯D(31.68%)、β-石竹烯(16.07%)和(E)-β-法尼烯(7.99%)。为了评价挥发油的抗氧化活性，进行了6项抗氧化实验。结果表明，挥发油具有明显的2,2′-氮基-双(3-乙基苯并噻唑-6-磺酸)二铵盐和羟基自由基清除能力。此外，还测定了挥发油对4种常见病原菌的抑菌活性。结果表明，挥发油对大肠杆菌和产气菌具有较强的抑菌活性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Natural Product Research 化学-医药化学

CiteScore

5.10

自引率

9.10%

发文量

605

审稿时长

2.1 months

期刊介绍： The aim of Natural Product Research is to publish important contributions in the field of natural product chemistry. The journal covers all aspects of research in the chemistry and biochemistry of naturally occurring compounds. The communications include coverage of work on natural substances of land and sea and of plants, microbes and animals. Discussions of structure elucidation, synthesis and experimental biosynthesis of natural products as well as developments of methods in these areas are welcomed in the journal. Finally, research papers in fields on the chemistry-biology boundary, eg. fermentation chemistry, plant tissue culture investigations etc., are accepted into the journal. Natural Product Research issues will be subtitled either ""Part A - Synthesis and Structure"" or ""Part B - Bioactive Natural Products"". for details on this , see the forthcoming articles section. All manuscript submissions are subject to initial appraisal by the Editor, and, if found suitable for further consideration, to peer review by independent, anonymous expert referees. All peer review is single blind and submission is online via ScholarOne Manuscripts.