Amna Sarfraz, Muhammad Imran Hussain, Ramisha Ibtisam, Annum Maha, Saher Asghar, Khizra Zubair, Khurram Sarfraz
{"title":"Synergistic effect of Moringa oleifera and Allium sativum on BMI and lipid profile: A randomized controlled trial.","authors":"Amna Sarfraz, Muhammad Imran Hussain, Ramisha Ibtisam, Annum Maha, Saher Asghar, Khizra Zubair, Khurram Sarfraz","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>We investigate the synergistic effect of Moringa oleifera and Allium sativum on hyperlipidemic patients. It was a randomized controlled trial. The sample size of this study was 60 patients who were divided into four equal groups (n=15) through a random sampling technique. Pre assessment of all participants was conducted at the start of the research. The control group (group A) received atorvastatin 10mg QD as well as placebo capsules. The treatment group 1 (group B) received atorvastatin 10mg QD as well as Moringa oleifera 2g (capsule 1g BID). Treatment group 2 (group C) received atorvastatin 10mg QD as well as Allium sativum 2g (capsule 1g BID). Lastly, treatment group 3 (Group D) received atorvastatin 10mg QD as well as combined Moringa oleifera 2g (capsule 1g BID) and Allium sativum 2g (capsule 1g BID). After an intervention of 45 days, post assessment was conducted. The results showed total cholesterol and triglycerides and low-density lipoprotein of participants of treatment group 3 who received both MO and AS were statistically significant (p<0.05). The group that was on Moringa oleifera supplements alone was found to be statistically significant (p<0.05). This study concluded that Moringa oleifera and Allium sativum considerably improved the BMI and lipid profile of participants.</p>","PeriodicalId":19971,"journal":{"name":"Pakistan journal of pharmaceutical sciences","volume":null,"pages":null},"PeriodicalIF":0.7000,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Pakistan journal of pharmaceutical sciences","FirstCategoryId":"3","ListUrlMain":"","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"PHARMACOLOGY & PHARMACY","Score":null,"Total":0}
引用次数: 0
Abstract
We investigate the synergistic effect of Moringa oleifera and Allium sativum on hyperlipidemic patients. It was a randomized controlled trial. The sample size of this study was 60 patients who were divided into four equal groups (n=15) through a random sampling technique. Pre assessment of all participants was conducted at the start of the research. The control group (group A) received atorvastatin 10mg QD as well as placebo capsules. The treatment group 1 (group B) received atorvastatin 10mg QD as well as Moringa oleifera 2g (capsule 1g BID). Treatment group 2 (group C) received atorvastatin 10mg QD as well as Allium sativum 2g (capsule 1g BID). Lastly, treatment group 3 (Group D) received atorvastatin 10mg QD as well as combined Moringa oleifera 2g (capsule 1g BID) and Allium sativum 2g (capsule 1g BID). After an intervention of 45 days, post assessment was conducted. The results showed total cholesterol and triglycerides and low-density lipoprotein of participants of treatment group 3 who received both MO and AS were statistically significant (p<0.05). The group that was on Moringa oleifera supplements alone was found to be statistically significant (p<0.05). This study concluded that Moringa oleifera and Allium sativum considerably improved the BMI and lipid profile of participants.
期刊介绍:
Pakistan Journal of Pharmaceutical Sciences (PJPS) is a peer reviewed multi-disciplinary pharmaceutical sciences journal. The PJPS had its origin in 1988 from the Faculty of Pharmacy, University of Karachi as a biannual journal, frequency converted as quarterly in 2005, and now PJPS is being published as bi-monthly from January 2013.
PJPS covers Biological, Pharmaceutical and Medicinal Research (Drug Delivery, Pharmacy Management, Molecular Biology, Biochemical, Pharmacology, Pharmacokinetics, Phytochemical, Bio-analytical, Therapeutics, Biotechnology and research on nano particles.