H. Al-Sagur , S. Komathi , A. Khan , A.G. Gurek , A. Hassan
{"title":"A Novel Glucose Sensor Using Lutetium Phthalocyanine as Redox Mediator in Reduced Graphene Oxide Conducting Polymer Multifunctional Hydrogel","authors":"H. Al-Sagur , S. Komathi , A. Khan , A.G. Gurek , A. Hassan","doi":"10.1016/j.protcy.2017.04.078","DOIUrl":null,"url":null,"abstract":"<div><p>Herein, we report a scalable synthesis of multifunctional conducting polyacrylic acid (PAA) hydrogel (MFH) integrated with reduced grapheme oxide (rGO), vinyl substituted polyaniline (VS-PANI) and lutetium phthalocyanine (LuPc<sub>2</sub>) as three dimensional robust matrix for glucose oxidase (GOx) immobilization (PAA-rGO/VS-PANI/LuPc<sub>2</sub>/GOx-MFH). We have integrated the multicomponents such as PAA with rGO, VS-PANI through free radical polymerization using methylene bis-acrylamide, ammonium persulphate as the cross linker and initiator. The LuPc<sub>2</sub> was then doped to form multifunctional hydrogel (PAA-rGO/VS-PANI/LuPc<sub>2</sub>-MFH). Finally, biosensor was fabricated by immobilizing GOx into PAA-rGO/VS-PANI/LuPc<sub>2</sub>-MFH and subsequently used for electrochemical detection of glucose.</p></div>","PeriodicalId":101042,"journal":{"name":"Procedia Technology","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.protcy.2017.04.078","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Procedia Technology","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2212017317300798","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1
Abstract
Herein, we report a scalable synthesis of multifunctional conducting polyacrylic acid (PAA) hydrogel (MFH) integrated with reduced grapheme oxide (rGO), vinyl substituted polyaniline (VS-PANI) and lutetium phthalocyanine (LuPc2) as three dimensional robust matrix for glucose oxidase (GOx) immobilization (PAA-rGO/VS-PANI/LuPc2/GOx-MFH). We have integrated the multicomponents such as PAA with rGO, VS-PANI through free radical polymerization using methylene bis-acrylamide, ammonium persulphate as the cross linker and initiator. The LuPc2 was then doped to form multifunctional hydrogel (PAA-rGO/VS-PANI/LuPc2-MFH). Finally, biosensor was fabricated by immobilizing GOx into PAA-rGO/VS-PANI/LuPc2-MFH and subsequently used for electrochemical detection of glucose.