Material and Design Toolkit for Drug Delivery: State of the Art, Trends, and Challenges

IF 8.3 2区 材料科学 Q1 MATERIALS SCIENCE, MULTIDISCIPLINARY
Monireh Esmaeili Rad, Caner Soylukan, Prabir Kumar Kulabhusan, Beyza Nur Günaydın and Meral Yüce*, 
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引用次数: 0

Abstract

The nanomaterial and related toolkit have promising applications for improving human health and well-being. Nanobased drug delivery systems use nanoscale materials as carriers to deliver therapeutic agents in a targeted and controlled manner, and they have shown potential to address issues associated with conventional drug delivery systems. They offer benefits for treating various illnesses by encapsulating or conjugating biological agents, chemotherapeutic drugs, and immunotherapeutic agents. The potential applications of this technology are vast; however, significant challenges exist to overcome such as safety issues, toxicity, efficacy, and insufficient capacity. This article discusses the latest developments in drug delivery systems, including drug release mechanisms, material toolkits, related design molecules, and parameters. The concluding section examines the limitations and provides insights into future possibilities.

Abstract Image

Abstract Image

药物输送的材料和设计工具包:现状、趋势和挑战。
纳米材料和相关工具包在改善人类健康和福祉方面具有很好的应用前景。纳米药物递送系统使用纳米材料作为载体,以靶向和受控的方式递送治疗剂,并且它们已经显示出解决传统药物递送系统相关问题的潜力。它们通过包封或结合生物制剂、化疗药物和免疫治疗剂,为治疗各种疾病提供益处。这项技术的潜在应用是巨大的;然而,存在着重大的挑战需要克服,如安全问题、毒性、有效性和能力不足。本文讨论了药物释放系统的最新进展,包括药物释放机制、材料工具箱、相关设计分子和参数。结论部分考察了局限性,并提供了对未来可能性的见解。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
ACS Applied Materials & Interfaces
ACS Applied Materials & Interfaces 工程技术-材料科学:综合
CiteScore
16.00
自引率
6.30%
发文量
4978
审稿时长
1.8 months
期刊介绍: ACS Applied Materials & Interfaces is a leading interdisciplinary journal that brings together chemists, engineers, physicists, and biologists to explore the development and utilization of newly-discovered materials and interfacial processes for specific applications. Our journal has experienced remarkable growth since its establishment in 2009, both in terms of the number of articles published and the impact of the research showcased. We are proud to foster a truly global community, with the majority of published articles originating from outside the United States, reflecting the rapid growth of applied research worldwide.
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