Prognostic Factors for Hyperglycemia in Patients Receiving Chemotherapy.

IF 2.4 3区医学 Q1 NURSING

Cancer Nursing Pub Date : 2025-03-01 Epub Date: 2023-11-22 DOI:10.1097/NCC.0000000000001271

Jiyeong Kim, Kyung Hee Lim

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引用次数: 0

Abstract

Background: Approximately 10% to 30% of patients who receive chemotherapy experience hyperglycemia, which can affect the adverse reactions and treatment efficacy of chemotherapy. However, there is a paucity of research to explore the factors affecting hyperglycemia and include them in nursing interventions.

Objective: The aim of this study was to understand the prognostic factors of hyperglycemia in cancer patients on chemotherapy.

Methods: This retrospective, descriptive study included 134 adult patients with cancer receiving chemotherapy at Keimyeng University Dongsan Hospital in Daegu between July 1, 2021, and March 31, 2022. Data were analyzed using frequency, percentage, average, and standard deviation statistics and compared by t test, χ 2 test, and logistic regression analysis.

Results: Logistic regression analysis revealed that sex (male) (95% confidence interval [CI], 7.24-745.49; odds ratio [OR], 73.48); education (95% CI, 4.02-201.59; OR, 28.46); exercise durations of 30 to 60 minutes (95% CI, 0.00-0.06; OR, 0.01), 60 to 90 minutes (95% CI, 0.00-0.05, OR = 0.01), and ≥90 minutes (95% CI, 0.00-0.42; OR, 0.03); exercise amount ≥ 2000 kcal/wk (95% CI, 0.01-0.77; OR, 0.06); and daily fat (95% CI, 1.02-1.14; OR, 1.08), protein (95% CI, 0.82-0.95; OR, 0.88), and seaweed (95% CI, 0.85-0.99; OR, 0.92) intake were significant predictors of hyperglycemia.

Conclusion: The prognostic factors of hyperglycemia should be included in nursing interventions to prevent and manage hyperglycemia, which in turn may help reduce adverse reactions related to chemotherapy and improve treatment efficacy.

Implications for practice: To prevent and manage hyperglycemia in patients on chemotherapy, prognostic factors, including exercise and protein, fat, and seaweed consumption, should be considered in nursing interventions. Particularly, in men and patients with low education levels who are at a high risk of hyperglycemia, nursing interventions for diet and exercise should be individualized.

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化疗患者高血糖的预后因素。

背景:大约10% ~ 30%的化疗患者会出现高血糖，高血糖会影响化疗的不良反应和治疗效果。然而，研究高血糖的影响因素并将其纳入护理干预的研究却很少。目的:本研究旨在了解癌症化疗患者高血糖的预后因素。方法:这项回顾性描述性研究纳入了2021年7月1日至2022年3月31日期间在大邱启明大学东山医院接受化疗的134名成年癌症患者。资料分析采用频率、百分比、平均值和标准差统计，比较采用t检验、χ2检验和logistic回归分析。结果:Logistic回归分析显示性别(男性)(95%置信区间[CI]， 7.24-745.49;优势比[OR]， 73.48);教育(95% CI, 4.02-201.59;或者,28.46);运动时间为30 - 60分钟(95% CI, 0.00-0.06;OR, 0.01)， 60 ~ 90分钟(95% CI, 0.00-0.05, OR = 0.01)和≥90分钟(95% CI, 0.00-0.42;或者,0.03);运动量≥2000千卡/周(95% CI, 0.01-0.77;或者,0.06);和日脂肪(95% CI, 1.02-1.14;OR, 1.08)，蛋白质(95% CI, 0.82-0.95;OR, 0.88)和海藻(95% CI, 0.85-0.99;OR(0.92)是高血糖的重要预测因子。结论:应将影响高血糖预后的因素纳入护理干预，预防和管理高血糖，从而减少化疗相关不良反应，提高治疗效果。实践意义:为了预防和控制化疗患者的高血糖，在护理干预中应考虑预后因素，包括运动和蛋白质、脂肪和海藻的摄入。特别是，对于男性和低教育水平的高血糖高危患者，饮食和运动方面的护理干预应个体化。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Cancer Nursing 医学-护理

CiteScore

4.80

自引率

3.80%

发文量

244

审稿时长

6-12 weeks

期刊介绍： Each bimonthly issue of Cancer Nursing™ addresses the whole spectrum of problems arising in the care and support of cancer patients--prevention and early detection, geriatric and pediatric cancer nursing, medical and surgical oncology, ambulatory care, nutritional support, psychosocial aspects of cancer, patient responses to all treatment modalities, and specific nursing interventions. The journal offers unparalleled coverage of cancer care delivery practices worldwide, as well as groundbreaking research findings and their practical applications.