{"title":"Additive manufacturing of magnesium alloys and its biocompatibility","authors":"Pralhad Pesode, Shivprakash Barve","doi":"10.1016/j.bprint.2023.e00318","DOIUrl":null,"url":null,"abstract":"<div><p><span><span>A new class of alloys called magnesium-based alloys has the unique property of being biodegradable inside the humans and animals. In addition to being biodegradable, Mg-based alloys are suitable materials for creating medical implants<span><span> for utilization in orthopaedic and </span>traumatology<span><span> therapies due to their inherent biocompatibility and bone-like density. Due to the combination of bioimplant design and manufacturing techniques appropriate to particular applications, </span>additive manufacturing<span> (AM) and three-dimensional (3D) printing now offer a potential production approach. Magnesium (Mg) use in biomedical field is rising year by year due to rising needs in the biomedical sector. In this biomedical field, additive manufacturing (AM) gives you the freedom to create components with complicated shapes and good dimensional stability. Additionally, it opens up a new opportunity for using unique component architectures, expanding the uses for magnesium alloy. The numerous AM techniques utilised to create biomedical implants from magnesium-based alloys were rigorously examined in current study, along with the materials, microscopic structure, </span></span></span></span>mechanical characteristics<span>, biocompatibility, biodegradability<span> and antibacterial properties. It was observed that </span></span></span>powder bed fusion<span> (PBF) is a very good method for manufacturing magnesium implants<span> as topology can be carefully controlled in powder bed fusion process. It was observed that selective laser melting<span><span> process offer more functionality than selective laser sintering process because Mg is completely melted and penetrated deeply during selective laser melting process. Selective laser melting has advantages such as smaller grains, a homogenous phase distribution, an improved solid solution </span>rapid solidification and considerable cooling rates. In this article the difficulties and problems associated with AM methods were recognised from the viewpoints of bioimplant design, characteristics, and applications. Critical exploration is also done on the difficulties and potential of AM of magnesium alloys.</span></span></span></p></div>","PeriodicalId":37770,"journal":{"name":"Bioprinting","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2023-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Bioprinting","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2405886623000611","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"Computer Science","Score":null,"Total":0}
引用次数: 0
Abstract
A new class of alloys called magnesium-based alloys has the unique property of being biodegradable inside the humans and animals. In addition to being biodegradable, Mg-based alloys are suitable materials for creating medical implants for utilization in orthopaedic and traumatology therapies due to their inherent biocompatibility and bone-like density. Due to the combination of bioimplant design and manufacturing techniques appropriate to particular applications, additive manufacturing (AM) and three-dimensional (3D) printing now offer a potential production approach. Magnesium (Mg) use in biomedical field is rising year by year due to rising needs in the biomedical sector. In this biomedical field, additive manufacturing (AM) gives you the freedom to create components with complicated shapes and good dimensional stability. Additionally, it opens up a new opportunity for using unique component architectures, expanding the uses for magnesium alloy. The numerous AM techniques utilised to create biomedical implants from magnesium-based alloys were rigorously examined in current study, along with the materials, microscopic structure, mechanical characteristics, biocompatibility, biodegradability and antibacterial properties. It was observed that powder bed fusion (PBF) is a very good method for manufacturing magnesium implants as topology can be carefully controlled in powder bed fusion process. It was observed that selective laser melting process offer more functionality than selective laser sintering process because Mg is completely melted and penetrated deeply during selective laser melting process. Selective laser melting has advantages such as smaller grains, a homogenous phase distribution, an improved solid solution rapid solidification and considerable cooling rates. In this article the difficulties and problems associated with AM methods were recognised from the viewpoints of bioimplant design, characteristics, and applications. Critical exploration is also done on the difficulties and potential of AM of magnesium alloys.
期刊介绍:
Bioprinting is a broad-spectrum, multidisciplinary journal that covers all aspects of 3D fabrication technology involving biological tissues, organs and cells for medical and biotechnology applications. Topics covered include nanomaterials, biomaterials, scaffolds, 3D printing technology, imaging and CAD/CAM software and hardware, post-printing bioreactor maturation, cell and biological factor patterning, biofabrication, tissue engineering and other applications of 3D bioprinting technology. Bioprinting publishes research reports describing novel results with high clinical significance in all areas of 3D bioprinting research. Bioprinting issues contain a wide variety of review and analysis articles covering topics relevant to 3D bioprinting ranging from basic biological, material and technical advances to pre-clinical and clinical applications of 3D bioprinting.