Skin Prick Automated Test device offers more reliable allergy test results compared to a manual skin prick test.

IF 4.8 2区医学 Q1 OTORHINOLARYNGOLOGY

Rhinology Pub Date : 2024-04-01 DOI:10.4193/Rhin23.330

S F Seys, K Roux, C Claes, L Van Cappellen, L Werpin, D Loeckx, H Sebrechts, S Gorris, L Van Gerven

{"title":"Skin Prick Automated Test device offers more reliable allergy test results compared to a manual skin prick test.","authors":"S F Seys, K Roux, C Claes, L Van Cappellen, L Werpin, D Loeckx, H Sebrechts, S Gorris, L Van Gerven","doi":"10.4193/Rhin23.330","DOIUrl":null,"url":null,"abstract":"Background: The skin prick test (SPT) is the gold standard for identifying allergic sensitization in individuals suspected of inhalant allergy. A novel device, SPAT or Skin Prick Automated Test, that enables more standardized allergy testing has been developed. Previous research has shown reduced intra-subject variability of histamine wheals by SPAT.Objective: This study aimed to evaluate within-test agreement (% of patients with consistent test results) to detect sensitization to common inhalant allergens when a SPT is executed automated by SPAT or by manual SPT (SPMT) procedure.Methods: The 110 volunteers prospectively enrolled underwent both SPAT and SPMT with 3 pricks of house dust mite, timothy grass and birch, 2 pricks of histamine and 1 prick of glycerol. The proportion of consistent (3x positive â€\" 3 x negative) and inconsistent (2x positive/negative â€\" 1x positive/negative) test results were analysed.Results: The proportion of inconsistent test results was significantly lower in the SPAT compared to the SPMT group. The delta histamine to control pricks was significantly higher in SPAT compared to SPMT group. Coefficient of variation was lower in SPAT compared to SPMT for house dust mite, timothy grass, birch pollen. Visual analogue scale for discomfort was significantly lower in SPAT compared to SPMT group.Conclusion: SPAT showed a 34% reduction in the number of inconsistent test results compared to manual SPT with common inhalant allergens. Patient experience is significantly improved when an allergy test is performed by SPAT compared to a manual SPT.","PeriodicalId":21361,"journal":{"name":"Rhinology","volume":" ","pages":"216-222"},"PeriodicalIF":4.8000,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Rhinology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.4193/Rhin23.330","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"OTORHINOLARYNGOLOGY","Score":null,"Total":0}

引用次数: 0

Abstract

Background: The skin prick test (SPT) is the gold standard for identifying allergic sensitization in individuals suspected of inhalant allergy. A novel device, SPAT or Skin Prick Automated Test, that enables more standardized allergy testing has been developed. Previous research has shown reduced intra-subject variability of histamine wheals by SPAT.

Objective: This study aimed to evaluate within-test agreement (% of patients with consistent test results) to detect sensitization to common inhalant allergens when a SPT is executed automated by SPAT or by manual SPT (SPMT) procedure.

Methods: The 110 volunteers prospectively enrolled underwent both SPAT and SPMT with 3 pricks of house dust mite, timothy grass and birch, 2 pricks of histamine and 1 prick of glycerol. The proportion of consistent (3x positive â€" 3 x negative) and inconsistent (2x positive/negative â€" 1x positive/negative) test results were analysed.

Results: The proportion of inconsistent test results was significantly lower in the SPAT compared to the SPMT group. The delta histamine to control pricks was significantly higher in SPAT compared to SPMT group. Coefficient of variation was lower in SPAT compared to SPMT for house dust mite, timothy grass, birch pollen. Visual analogue scale for discomfort was significantly lower in SPAT compared to SPMT group.

Conclusion: SPAT showed a 34% reduction in the number of inconsistent test results compared to manual SPT with common inhalant allergens. Patient experience is significantly improved when an allergy test is performed by SPAT compared to a manual SPT.

查看原文本刊更多论文

与手动皮肤刺痛测试相比，皮肤刺痛自动测试设备提供了更可靠的过敏测试结果。

背景:皮肤点刺试验(SPT)是鉴别疑似吸入性过敏患者的过敏致敏性的金标准。一种新的设备，皮肤点刺自动测试，使更标准化的过敏测试已经开发出来。先前的研究已经表明，由唾液引起的组胺轮的受试者内部变异性降低。目的:本研究旨在评估测试内一致性(测试结果一致的患者的百分比)，以检测通过自动SPT或手动SPT (SPMT)程序执行SPT时对常见吸入性过敏原的致敏性。方法:前瞻性纳入的110名志愿者分别进行了spt和SPMT治疗，其中屋尘螨、山楂草和桦木3针，组胺2针，甘油1针。分析检测结果一致(3x阳性- 3x阴性)和不一致(2x阳性/阴性- 1x阳性/阴性)的比例。结果:与SPMT组相比，SPMT组检测结果不一致的比例明显降低。与SPMT组相比，SPMT组控制刺痛的δ组胺显著升高。屋尘螨、草、桦树花粉的SPMT变异系数较低。与SPMT组相比，SPMT组不适的视觉模拟评分明显降低。结论:与使用常见吸入性过敏原的手动SPT相比，SPT显示不一致测试结果的数量减少了34%。与手动SPT相比，使用SPT进行过敏试验可显著改善患者体验。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Rhinology 医学-耳鼻喉科学

CiteScore

15.80

自引率

9.70%

发文量

135

审稿时长

6-12 weeks

期刊介绍： Rhinology serves as the official Journal of the International Rhinologic Society and is recognized as one of the journals of the European Rhinologic Society. It offers a prominent platform for disseminating rhinologic research, reviews, position papers, task force reports, and guidelines to an international scientific audience. The journal also boasts the prestigious European Position Paper in Rhinosinusitis (EPOS), a highly influential publication first released in 2005 and subsequently updated in 2007, 2012, and most recently in 2020. Employing a double-blind peer review system, Rhinology welcomes original articles, review articles, and letters to the editor.