Diffuse alveolar hemorrhage with chronic thyroiditis in an advanced-age adult

Masanori Fujii, Nobuaki Miyahara, Yasushi Tanimoto, Nagio Takigawa, Masahiro Tabata, Arihiko Kanehiro, Katsuyuki Kiura, Mitsune Tanimoto
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引用次数: 5

Abstract

Idiopathic pulmonary hemosiderosis (IPH) is one of the rare causes of diffuse alveolar hemorrhage (DAH), and usually occurs in children. The mechanism underlying this disease development has not been defined. During the acute phase, death due to massive alveolar hemorrhage and subsequent severe respiratory failure with multiple organ failure often occurs. We report a case of IPH which occurred in an advanced-aged adult during following thyroidectomy for chronic thyroiditis. Following surgery this 83-year-old male developed acute onset dyspnea and pulmonary hemorrhage. In a search for underlying causes, no disorders were found and the only finding was the presence of anti-thyroid antibody. Systemic corticosteroid therapy was effective and he fully recovered. To our knowledge, this is the second documentation of IPH in association with chronic thyroiditis.

弥漫性肺泡出血并发慢性甲状腺炎1例
特发性肺含铁血黄素沉着症(IPH)是弥漫性肺泡出血(DAH)的罕见病因之一,多见于儿童。这种疾病发展的机制尚未明确。在急性期,经常发生因大量肺泡出血和随后的严重呼吸衰竭并多器官衰竭而死亡。我们报告一例IPH发生在一个老年成人在甲状腺切除术后慢性甲状腺炎。手术后,这名83岁男性出现急性呼吸困难和肺出血。在寻找潜在原因时,没有发现任何疾病,唯一的发现是抗甲状腺抗体的存在。全身皮质类固醇治疗有效,患者完全康复。据我们所知,这是第二份IPH与慢性甲状腺炎相关的文献。
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