Basaloid skin tumours: Mimics of basal cell carcinoma

Current diagnostic pathology Pub Date : 2007-08-01 DOI:10.1016/j.cdip.2007.05.003

R.A. Carr, D.S.A. Sanders

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引用次数: 31

Abstract

This article is the second of two papers relating to the histopathological diagnosis of basaloid skin tumours and the uses of immunohistochemistry. The first paper focused on basal cell carcinoma and variants, and this paper will concentrate on tumours that may be confused with basal cell carcinoma. The basaloid tumours of the skin can be classified according to the general classification of skin tumours, including epidermal, appendageal (hair follicle and sweat gland derived) and others including cutaneous metastases. The areas of discussion concentrate on the distinction of basal cell carcinoma from basaloid squamous cell carcinoma, infiltrative basaloid tumours (desmoplastic trichoepithelioma, infiltrative basal cell carcinoma, microcystic adnexal carcinoma and eccrine epithelioma), follicular induction overlying dermatofibroma, basaloid proliferations in naevus sebaceus, trichoepithelioma, trichoblastoma, trichoepithelioma-like basal cell carcinoma, pilomatrical tumours and selected sweat gland tumours. The immunohistochemical stains that may be of use in differential diagnosis are discussed, including BerEP4, epithelial membrane antigen, CD10, bcl-2, Cam5.2, CK20, carcinoembryonic antigen and p53.

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基底样皮肤肿瘤:模拟基底细胞癌

这篇文章是两篇关于皮肤基底细胞肿瘤的组织病理学诊断和免疫组织化学应用的论文中的第二篇。第一篇论文集中在基底细胞癌和变异，这篇论文将集中在肿瘤可能与基底细胞癌混淆。皮肤基底细胞瘤可根据皮肤肿瘤的一般分类进行分类，包括表皮性、附属性(源自毛囊和汗腺)和其他包括皮肤转移性肿瘤。讨论的领域集中在基底细胞癌与基底样鳞状细胞癌、浸润性基底样肿瘤(韧带增殖性毛上皮瘤、浸润性基底细胞癌、微囊性附件癌和内分泌上皮瘤)、皮肤纤维瘤上的卵泡诱导、皮脂腺痣、毛上皮瘤、毛上皮细胞瘤、毛上皮瘤样基底细胞癌、毛瘤肿瘤和选择性汗腺肿瘤的区别。讨论了可能用于鉴别诊断的免疫组化染色，包括BerEP4、上皮膜抗原、CD10、bcl-2、Cam5.2、CK20、癌胚抗原和p53。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Current diagnostic pathology

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