The use of immunohistochemistry in the differential diagnosis of common epithelial tumours of the skin

Abstract

Immunohistochemistry may be useful in the differential diagnosis of epithelial skin tumours in day-to-day practice. This article lists commonly available antibodies, summarizes immunostaining patterns reported in the literature for this group of tumours, highlights immunostaining patterns encountered in normal skin, and emphasizes the immunomarkers that the authors have found to be of particular value. The use of small immunopanels in different diagnostic settings is illustrated.