GH responsiveness to GHRH in obese children before and after weight loss.

Abstract

It is well known that obese children show impaired growth hormone (GH) responses to provocative stimuli, such as insulin-induced hypoglycemia (l) , arginine (2) and sleep (2). In addition, Pertzelan et al. (3) have recently demonstrated that obese children show an impaired GH response to GH releasing hormone (GHRH). In this work, we compare GH response to GHRH in obese children before and after weight loss.