[The 4th complement factor (C4) and t haplotypes in wild mice].

U Vergara, M León, M Santos, C Zúñiga
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Abstract

Five different lines of tailless mice bearing different t recessive haplotypes (tAn, tMo, tRa, tLa and tQu) have been established in our laboratory and maintained in combination with the brachury chromosome (T). These t haplotypes were derived from widely separated Chilean wild mouse populations. The immunoelectrophoretic typing for Ss and Slp isotypic variants of C4 showed that all lines had the Ss-High. Slp-negative phenotype suggesting that the t haplotypes might be associated with similar S regions of the major histocompatibility system of the mouse.

[野生小鼠的第4补体因子(C4)和t单倍型]。
我们在实验室建立了5个不同的无尾小鼠系,它们具有不同的t隐性单倍型(tAn、tMo、tRa、tLa和tQu),并与短染色体(t)结合,这些t单倍型来源于广泛分离的智利野生小鼠种群。对C4的Ss和Slp同型变异体进行免疫电泳分型,结果表明所有系均具有Ss- high。slp阴性表型表明t单倍型可能与小鼠主要组织相容性系统的相似S区有关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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