Haemotobiochemical changes and management of post-partum fatty liver syndrome in Malabari goats

Kalakappa Kalakappa, S. Ajithkumar, Biju P. Habeeb, S. Senthil Murugan, Anjaly Krishnan, P. Vinu David, O. K. Sindhu, N. Madhavan Unny
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Abstract

The fatty liver syndrome was confirmed by haemotobiochemical and hepatic ultrasonographic investigations in 12 Malabari goats within six weeks after kidding. Animals were divided into two groups with six does each which received two different treatments. Ketonex bolus, which contains nicotinic acid, disodium hydrogen phosphate, and live yeast was given to the goats in Group I. The animals in Group II received syrup Bexoliv, which contains tricholine citrate, methionine, inositol, vitamin E, biotin, selenium, silymarin, iron, copper, and B12. In addition to this, animals of both groups received glycerin orally. On the fifteenth day of treatment, the animals were reevaluated. Six apparently healthy adult female goats within six weeks of kidding were selected as control. Before treatment, the neutrophil count showed a significant increase and lymphocyte and monocyte counts showed a decrease in the study groups. Blood beta-hydroxybutyrate (βHB), serum non-esterified free fatty acids (NEFA) and serum urea nitrogen (SUN) levels showed a significant increase before treatment and reduced after treatment among both groups. Hepatic ultrasonography showed hyperechogenicity of parenchyma before treatment when compared to after treatment. The animals showed improvement with both treatments.
马拉巴里山羊产后脂肪肝综合征的血液生化变化及处理
对12只马拉巴里山羊进行了6周内的血液生化和肝脏超声检查,证实了脂肪肝综合征。动物被分成两组,每组6只,接受两种不同的治疗。第1组给予含烟酸、磷酸氢二钠和活酵母的酮酮丸,第2组给予含枸橼酸tricholine、蛋氨酸、肌醇、维生素E、生物素、硒、水飞蓟素、铁、铜和B12的Bexoliv糖浆。除此之外,两组动物均口服甘油。在治疗的第15天,对动物进行重新评估。选取6只在开玩笑6周内明显健康的成年母山羊作为对照。治疗前,研究组中性粒细胞计数明显增加,淋巴细胞和单核细胞计数明显减少。两组患者血清β -羟基丁酸(βHB)、血清非酯化游离脂肪酸(NEFA)和血清尿素氮(SUN)水平均在治疗前显著升高,治疗后显著降低。与治疗后比较,治疗前肝脏超声显示实质高回声。两种治疗方法都对动物有改善。
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